Epidemiology lung cancer

Lemen RA. 1986. Occupationally induced lung cancer epidemiology. In Merchant JA, ed. Occupational respiratory diseases. U.S. Department of Health and Human Services 629-656. 

Shekelle, R.B. et al.. Serum cholesterol, beta-carotene, and risk of lung cancer. Epidemiology, 3 (4), 282,1992. 

Archer V, Radford E, Axelson O. 1979. Radon daughter cancer in man factors in exposure-response relationships at low levels. In Conference workshop on lung cancer epidemiology and industrial applications of sputum cytology. Golden, CO Colorado School of Mines... 

This meeting was not a discussion of the toxicity of lead, nor a congress in analytical chemistry, or lung cancer epidemiology, nor a confrontation of the possible or needed refinements of the Ames test. Other recent meetings have been organized on these subjects and we are happy that several of the participants actively participated to those discussions, for example ... 

HEI (Health Effects Institute). 1999. Diesel Emissions and Lung Cancer Epidemiology and Quantitative Risk Assessment. Cambridge, MA Health Effects Institute. 

The replacement of asbestos fibers by other fibrous materials has raised similar health issues in relation to substitute materials. However, since lung cancer has a latency period of approximately 25 years, and since the fiber exposure levels in contemporary industries is far lower than those which prevailed half a century ago, the epidemiological data on most substitutes is insufficient. A possible exception is slag fibers for which several studies on worker populations are available over extended periods (44) some results show a substantial increase in lung cancer occurrence. Consequentiy, the toxicity of asbestos substitute fibers remains a subject of active investigation. 

However, so far, only a few small-scale epidemiological surveys have been carried out or started to study the possible influence of the exposure to Rn-222 progeny in dwellings on the etiology of lung cancer in the general population, and the evidence of these findings is inconclusive. 

Ellett, W. H. and N. S. Nelson, Epidemiology and risk assessment Testing models for radon-induced lung cancer, in Indoor Air and Human Health (R. B. Gammage and S. V. Kaye, eds) pp. 79-107, Lewis Publishers, Inc., Chelsea, Michigan (1985). 

A number of epidemiological studies have been conducted to evaluate the association between lung cancer and occupational exposure to acrylonitrile (Collins et al. 1989 Delzell and Monson 1982 Kiesselbach et al. 1979 O Berg 1980 O Berg et al. 1985). Flowever, many of the studies suffer from deficiencies such as an insufficient quantification of exposure, short follow-up, small and relatively youthful cohorts or lack of consideration of the effects of smoking, and the results of the studies are often inconsistent. 

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