Loops libraries

The methodology should prove useful to efficiently construct loop-libraries corresponding to exposed loop regions of proteins and thus may be useful to gain new insights into protein-protein interactions. 

Ring and Cohen use a simple GA in their program BLoop to generate loop libraries for proteins by building up overlapping sets of tetrapeptides found in the structure database. They represent each tetrapeptide by one of four letters U, K, Z, J which correspond symbolically to the path taken by the four... 

Loops are specially recorded audio files that are usually fairly short in duration. Loops are standard audio files that can be played back using just about any Windows-compatible media player (even the Windows Media Player). What makes a loop a loop is that it is recorded and structured so that when it is played back twice in a row, the end of the loop immediately and seamlessly leads back into the beginning of the loop. This means that most loops can be played over and over again infinitely, sounding as if it were a much longer continuous recording. Loops are normal. wav audio files and are commercially available from multimedia companies for use in loop-based music tools. ACID loops from Sonic Foundry contain a little more information than a typical. wav file (such as key and tempo information) that make them particularly easy to use in ACID. Sonic Foundry loop libraries can be used with many other multimedia applications (for example, video editing applications or Flash animation tools) and loops from other companies loop libraries can also be used in ACID. 

The basic routine when adding media to a project is to play back the project (or loop play a smaller portion of the project) and preview media files in the Explorer window one at a time (possibly using the arrow keys on your keyboard to move, pause, and preview through the files in a folder) until you find suitable loops. Of course, this isn t an entirely random process. As you become more familiar with your loop library, you ll be able to zero in on what you need much more quickly. 

There are literally dozens of places where you can get more media files to use as loops. The rest of this chapter is devoted to various sources for more loops, both commercial loops for sale and loops available for free on the Web. In all cases, you need to carefully read the license agreements to determine if you can use the loops legally in your own projects. In almost all cases, when you purchase loops from a loop library, you are also purchasing the rights to use these loops as well. This is often described as royalty-free, which means you can use them without paying additional royalties. It may be more difficult to assess the licensing and royalty situation of loops that are available for download from the Web. 

David supports his loop-library addiction by working as the technical editor at a leading video magazine. After hours, he has been collaborating electronically with a producer half-way around the world, scoring an edgy documentary for a cut of any eventual revenues, which no one but the producer actually believes will ever materialize. He currently resides in Chico, CA, and can be virtually visited at maxent.org/acidpower.html. 

Table 17.1 Phage-optimized sequences of Kunitz domain libraries primary binding loop...

In a sequential-modular program the executive program sets up the flow-sheet sequence, identifies the recycle loops, and controls the unit operation calculations interacting with the unit operations library, physical property data bank and the other sub-routines. It will also contain procedures for the optimum ordering the calculations and routines to promote... 

Construction effects The effects of construction were less pronounced than the effects of color. In general, cut pile carpets had larger absorbances across the entire spectrum than did loop pile carpets, but the positions of the characteristic absorption peaks were not affected. As for color, accurate calibration models could be developed on second-derivative spectra as long as sufficient variation in carpet construction was included in the library. 

McNaughton, B. R. Gareiss, P. C. Miller, B. L. Identification of a selective small-molecule ligand for HlV-l frameshift-inducing stem-loop RNA from an 11,325 member resin bound dynamoic combinatorial library. J. Am. Chem. Soc., 2007,129, 11306-11307. 

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