Long-term adverse effects

R53 may cause long-term adverse effects in the aquatic environment c... 

The relationship of these response curves to ambient air quality is shown by lines A, B, and C, which represent the maximum or any other chose percentile line from a display such as Fig. 4-10, which shows actual air quality. Where the air quality is poor (line A), essentially all the adverse effects displayed will occur. Where the air quality is good (line C), most of the intermediate and long-term adverse effects displayed will not occur. Where the air quality is between good and poor, some of the intermediate and long-term adverse effects will occur, but in an attenuated form compared with those of poor air quality. These concepts will be referred to later in this text when air quality standards are discussed. 

Hazardous air pollutants (HAPs) are substances that may cause immediate or long-term adverse effects on human health. HAPs can be gases, particulates, trace metals such as mercui y, and vapors such as benzene. For coal-fired power plants, the HAPs of most concern are metals such as mercury, arsenic, and vanadium. 

Budesonide is a high-potency glucocorticoid used in CD that has low systemic bioavailability when administered orally.23 The formulation releases budesonide in the terminal ileum for treatment of disease involving the ileum or ascending colon. Due to its reduced bioavailability, budesonide may prevent some long-term adverse effects in patients who have steroid-dependent IBD.23,24... 

If prophylactic medications are required, monitor patients for short- and long-term adverse effects ... 

Prevention of long-term adverse effects from dry eye... 

R51/53 Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Safety phrases a, b, c... 

Because information on possible long-term effects of the other irritant chemicals used in the Edgewood tests is sparse, this chapter focuses on the effects of mustard gas and two lacrimators, CS and CN. Information on the potential long-term adverse effects of these chemicals is derived from several sources first, observation of long-term disabilities in soldiers who were exposed to a single (in most cases) toxic concentration of irritant during World War I and in persons exposed in peacetime accidents or riot-control procedures second, studies of morbidity in workers chronically exposed to chemical irritants during their manufacture and third, studies in which experimental laboratory animals were exposed to selected chemicals by topical application, injection, or aerosol inhalation. 

These effects, if not promptly detected, may have long-term adverse effects on the patient s development by interfering at critical psychosocial stages and by compromising the ability to perform in school. These complications could offset any gains in psychosocial and school performance resulting from effective treatment of psychotic symptoms. 

Further information will need to be obtained about the possible long-term adverse effects of inhaled insulin. 

Due to their poor water solubility (less than 1 mg/L), disperse dyes have low acute ecological impact. Especially the acute toxicity to aquatic life is generally low. Nevertheless, according to the European chemicals legislation disperse dyes are classified as substances, that may cause long-term adverse effects in the aquatic environment [40,41], because they are not easily biodegradable and suspected of being potentially bioaccumulative due to their hydrophobicity. 

Barbiturates are also present in high concentrations in the breast milk of women who take them. Infants who consume this breast milk may experience side effects like excess sleepiness and lethargy. They may also experience withdrawal symptoms when weaned from breast milk. Long-term adverse effects of infant exposure to barbiturates in breast milk have not been well documented. However, the American Academy of Pediatrics cautions against breast-feeding while taking barbiturates because there may be risks to the infant. 

Indicates the rate at which a toxicant would be eliminated from the body affects its overall half-life Indicates for how long a compound would persist in the body and its potential for bioaccumulation, resulting in long-term adverse effects... 

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