Long interspersed nuclear elements

Domain involved in protein-protein interaction, originally described in transcription factors LINl, ISLl, and MED3 Long interspersed nuclear element Liquid-liquid extraction Lower limit of detection Lower limit of quantification Large nuclear ribonucleoprotein Limit of detection logjo of odds... 

DNA propellers. The a-mitochondriate Giardia is one of the most ancestral eukaryote. It has two telomeric G4 sequences a propeller-type parallel-stranded one with three G-tetrads, and a basket type anti-parallel-stranded one with two G-tetrads. Components of the G-quadruplexes can be readily exchanged by a cut and paste principle the chromosomal ends are kept capped [388]. The giardia genome is packed with retrotransposons (both LTR-, and non-LTR-types). The non-LTR-types are LINEs (long interspersed nuclear elements) with a single ORF... 

Epigenetic study subset of the NAS cohort, Boston, MA N=517 DNA methylation markers Alu, long-interspersed nuclear element (LINE-1) PbB = 4.1 xg/dl patellar Pb = 27.4 ppm tibial Pb = 20.5 Patellar Pb inversely associated with LINE-1 no association with either methylation marker for tibia Pb, PbB Wright et al. (2010)... 

Studies of overall genome composition based on reassociation kinetics (Simpson et ai, 1982 Cox et ai, 1990 Marx et a/., 2000) and analysis of fully sequenced bacterial artificial chromosome (BAC) clones from the 5. mansoni genome project show that platyhelminth genomes contain abundant highly and moderately repetitive sequence (Fig. 2.1). Much of the repetitive DNA comprises two classes of integrated mobile elements class I elements, which include long terminal repeat (LTR) retrotransposons and retroviruses, non-LTR retro-transposons and short interspersed nuclear elements (SINES) and transpose via an RNA intermediate, and class II elements (trans-posons), which transpose as DNA (Brindley et ai, 2003). Additionally, small dispersed or tandemly repeated sequences are common. A wide variety of these sequences have been isolated and characterized from a variety of taxa (Table 2.4). 

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