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Lividomycins

A, amikacin Ap, apramycin B, butirosin D, dibekacin G, gentamicin H, hygromycin I, isepam-icin K, kanamycin L, lividomycin N, netilmicin Ne, neomycin P, paromomycin R, ribostamycin S, sisomicin Sp, spectinomycin St, streptomycin T, tobramycin. [Pg.129]

Aminohippuric acid Bulk TLC CMA Silica (MeOH- pH 5.0, 12 kV NH4OH-MeOH Char mycin, lividomycin. amikacin, kanamycin. tobramycin, and sisomycin HPLC-OPA derivatization [148] HPLC-PAD [149-151] [1]... [Pg.149]

Interaction between -lactamase and intrinsic resistance Resistance to aminoglycosides Resistance to kanamycins Resistance to neomycins Resistance to streptomycin Resistance to gentamicin Resistance to lividomycin Resistance to tobramycin Resistance to BB-K8 Resistance to chloramphenicoi... [Pg.334]

Lividomycin phosphotransferase (LvPT) 5-Hydroxyl group of D-ribose is phosphorylated 200... [Pg.373]

Resistance to lividomycin. Lividomycin is a new aminoglycoside pentasaccharide antibiotic containing 2-deoxystreptamine (Figure 7.13) [200]. The activity of lividomycin against strains of Ps. aeruginosa is similar to that shown by streptomycin (Table 7.17). Lividomycin is not phosphory-lated by the neomycin kanamycin phosphotransferase because it lacks the 3 -hydroxyl group [212]. However, recently the presence was reported... [Pg.379]

Figure 7.13. Chemical structure of lividomycin A. The arrow indicates the site of action of the phosphorylating enzyme, lividomycin phosphotransferase... Figure 7.13. Chemical structure of lividomycin A. The arrow indicates the site of action of the phosphorylating enzyme, lividomycin phosphotransferase...
Table 7.16. ANTIBACTERIAL ACTIVITY OF LIVIDOMYCIN AGAINST SENSITIVE AND RESISTANT STRAINS OF PS. AERUGINOSA [200]... Table 7.16. ANTIBACTERIAL ACTIVITY OF LIVIDOMYCIN AGAINST SENSITIVE AND RESISTANT STRAINS OF PS. AERUGINOSA [200]...
Deoxylividomycin and 5"-amino-5"-deoxylividomycin have recently been synthesised [214] and, as expected, are not substrates for lividomycin phosphotransferase since they lack the hydroxyl moiety on the 5"-position of the D-ribose ring. Although these synthetic antibiotics are less potent than lividomycin, they show greater activity against strains producing the phosphorylating enzyme. [Pg.380]

The extrachromosomal nature of lividomycin resistance has not been proved conclusively. However, on storage loss of resistance to lividomycin along with inactivating enzyme from strains of Ps. aeruginosa occurs [198]. [Pg.380]

Two pseudopentasaccharides, lividomycin A and mannosylparomomycin, and 4" -0-a-D-mannopyranosyl-substituted derivatives of lividomycin B (27) and paromomycin I (25), respectively. They are produced by the same organism that produces... [Pg.310]

See other pages where Lividomycins is mentioned: [Pg.576]    [Pg.483]    [Pg.229]    [Pg.243]    [Pg.3]    [Pg.16]    [Pg.19]    [Pg.40]    [Pg.40]    [Pg.40]    [Pg.143]    [Pg.214]    [Pg.231]    [Pg.212]    [Pg.129]    [Pg.175]    [Pg.176]    [Pg.39]    [Pg.370]    [Pg.371]    [Pg.372]    [Pg.372]    [Pg.376]    [Pg.380]    [Pg.380]    [Pg.382]    [Pg.386]    [Pg.188]    [Pg.167]    [Pg.167]    [Pg.117]    [Pg.33]    [Pg.34]    [Pg.74]    [Pg.14]   


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Lividomycin

Lividomycin activity

Lividomycin antibacterial activity

Lividomycin inactivated

Lividomycin preparation

Lividomycin structure

Lividomycins 5-phosphate

Lividomycins activity

Lividomycins antibacterial activity

Lividomycins inactivated

Lividomycins inactivation

Lividomycins structure

Lividomycins synthesis

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