Liquid chromatography/mass spectrometry toxins

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Ciminiello, P, Aversano, C. D., Fattorusso, E., Mango, S., Tartaglione, L., Cangini, M., Pompei, M., Guerrini, R, Boni, L., and Pistocchi, R. Toxin profile of Alexandrium ostenfeldii (Dinophyceae) from the Northern Adriatic sea revealed by liquid chromatography-mass spectrometry, Toxicon, 47, 597-604, 2006. 

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Liquid chromatography-mass spectrometry (LC-MS) is a very promising analytical method for the MCs because it enables simultaneous separation and identification of cyanobacterial toxins in a mixture (Figure 40.2). Mass spectrometry, unlike UV spectroscopy, has the advantage that it can handle compounds that lack the UV chromophore. fit the case of MCs, the characteristic ion m/z 135 derived... 

Smith, G.A., et ai. (2003) Liquid chromatography mass spectrometry (LC-MS) based method for the analysis of algai toxins. In Proceedings—Water Quality Technology Conference, 554-558... 

Quilliam MA, Janecek M, Lawrence JF (1993) Characterization of the oxidation products of paralytic shellfish poisoning toxins by liquid chromatography/mass spectrometry. Rapid Commun Mass Spectrom 7 482-487... 

Turrell E, Stobo L, Lacaze JP, Piletsky S, Piletska E (2008) Optimization of hydrophilic interaction liquid chromatography/mass spectrometry and developmtait of solid-phase extraction for the determination of paralytic shellfish poistming toxins. J AOAC Int 91 1372-1386... 

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