Leishmanicidal effects

Curcumin possesses leishmanicidal effects in vitro and is more potent than the standard leishmaniasis drug, pentamidine. LD50 for leishmanicidal activity in vitro is found to be 37.6 3.5pM (Koide et al., 2002). 

Koide, T., Nose, M., Ogihara, Y., Yabu, Y. and Ohta, N. (2002) Leishmanicidal effect of curcumin in vitro. Biological and Pharmaceutical Bulletin 25, 131-133. 

Biological effects antitumor (Section 8.1), antifungal and antibacterial (Section 8.2), trypanocidal (Section 8.3.1), leishmanicidal (Section 8.3.2). 

Documented effects Compounds isolated from the roots exhibited leishmanicidal activity in vitro and inhibited growth of cultured malaria parasites, human lymphocytes, and human carcinoma cell lines (Sairafianpour et al. 2001). Compounds isolated from the aboveground parts exhibited cytotoxic activity against leukemia cells (Aoyagi et al. 2006). 

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