Leishmania enriettii parasite

Few studies have been conducted to date evaluating the effects of Pb exposure on host resistance to parasitic diseases, although one study examined the effect of Pb on the ability of mouse macrophages to kill Leishmania enriettii parasites in vitro [87], The authors found that 30-100 pM Pb acetate interfered with the killing ability of macrophages without producing macrophage cytotoxicity. 

Table 4 - Intracellular killing of Leishmania enriettii parasites by thioglycollate-induced peritoneal macrophages activated by IFNyor arabinogalactan [7]...

Landfear, S. M. and Wirth, D. F. (1984) Control of tubulin gene expression in the parasitic protozoan Leishmania enriettii. Nature 309 716-717. 

Peritoneal macrophages were parasitized with H-thymidine-labeled Leishmania enriettii promastigotes, followed by activation with EP-AG. The macrophages were lysed and the number of released viable parasites was quantified [7] (Tab. 4). 

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