Lectins receptor ligands

C-Type Lectins. Currently, the largest subfamily of lectins is the Ca -dependent (C-type) lectins. The Ca + is not directly involved with the CRD binding, but is important for the maintenance of a structure that permits receptor/ligand interactions. The C-type lectins are further subdivided as those family members that are membrane proteins (selec-tins, type II receptors, and transmembrane lectins with tandem CRDs) and that are soluble proteins (lecticansand collectins). Perhaps... 

The non-covalent interactions in many of natural compounds commonly referred as biomolecules are responsible for veiy important biological processes. The molecular recognition process in biological systems is observed between such species as receptor-ligand, antigen-antibody, sugar-lectin, DNA-protein, RNA-ribosome and others. The kinetics of the majority of glycan-protein interactions is fast and with dissociation... 

Binding proteins such as antibodies, receptors, and lectins may spontaneously aggregate in presence of bi- or multivalent specific ligands. This process, however, often results in assemblies that lack well-defined morphological and structural elements. 

Raff Is there any precedent for a lectin—ligand interaction on a receptor in any other system ... 

Importantly, the internal diffusion model for lectins binding to mucins is distinct from the classical lock and key model of ligand binding to a receptor. The internal... 

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