Leaves of Digitalis lanata

Leaves of Digitalis lanata Methyl ethyl ketone... 

A glycoside obtained from the leaves of Digitalis lanata (Scrophulariaceae). 

Leaves of Digitalis lanata gave two important cardiac glycosides. Give the structure, chemical name and uses. 

This was also confirmed by the correlation study of cardenolide contents in Digitalis lamta plants between ELISA and HPLC. The cardenolide contents in leaves of D. lanata cultivated in the field or hydroponic facilities were quantitatively analyzed by both ELISA and HPLC (Fig. 8). The content of digoxin equivalents in the leaves by ELISA correlated well to the total content of digoxin, deslanoside and lanatoside C as analyzed by HPLC. This indicates that the digoxin equivalents obtained by ELISA represent the total amount of digoxigenin glycosides present in the crude extracts of D. lanata. 

Instances of adulteration of P. lanceolata leaves with those of Digitalis lanata have been rarely reported (Slifman et al. 1998 Whitmore 1997). 

Homberger, M., Boettigheimer, U., Hillier-Kaiser, A. and Kreis, W. (2000) Purification and characterisation of the cardenolide-specific p-glucohydrolase CGH It from Digitalis lanata leaves. Plant Phi/siol. Biochem., 38, 929-36. 

The Digitalis lanata leaves from the first-year rosette are nowadays the most important source for extraction of Digitalis glycosides because the recent intensive research on dig-oxin has made this glycoside the first choice for therapy. 

Digitalis (foxglove) is a plant in which the leaves are the source of the active ingredients. Several species of the genus Digitalis are utilized, particularly D. purpurea and lanata. The plant was known botanically since the sixteenth century, but it was not until the... 

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