Lathyrus sativus

Lathyrus sativus (enzyme has inherent activities of agmatine iminohydrolase, putrescine transcarbamylase, ornithine transcarbamylase and carbamate kinase [1]) [1]... 

Srivenugopal, K.S. Adiga, P.R. Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. J. Biol. Chem., 256, 9532-9541 (1961)... 

Neurolathyrism occurs in some tropical countries as a result of consuming large quantities of the legume Lathyrus sativus, which contains a potent... 

Ricinus communis (Euphorbiaceae), Glycine max, Lathyrus sativus (Fabaceae), Sesamum indicum (Pedaliaceae), Hordeum vulgare (barley) (Poaceae)... 

Lathyrus sativus (chickling pea) (Fabaceae) a so-called famine plant consumed in India in the absence of other sustenance but with potential neurotoxic effects... 

L-BOAA (= P-A- Lathyrus sativus (babaceae) [seed] Induces BDNF expression... 

L-BOAA (= (3-jV-Oxalylamino-L-alanine) (amino acid) Lathyrus sativus (Fabaceae) [seed] [Induces NGF expression] (Non-NMDA Glu-R, Norepinephrine transport) [cytotoxic, excitatory, lathyrism (neuronal damage disease) in humans]... 

This is one of the eompounds (Figure 24.1) isolated from Lathyrus sativus, also ealled lathyrogenie substances. The toxieity of IDPN (and also of aziridines and tremorine)... 

In addition to compounds related to mimosine, other NPAAs are synthesized by transfer of an alanine residue catalysed by cysteine synthase, e.g. the formation of isoxazolin-5-on-2-yl-alanine in Lathyrus sativus (Ikegami et al, 1993). Moreover, partial purification of cysteine synthase from Allium tuberosum revealed that this enzyme also catalyses the formation of cysteine derivatives, such as S-allylcysteine (Ikegami et al, 1993). The various aspects of the formation of NPAAs by cysteine synthase are presented by Noji et al. (1993) and Ikegami and Murakoshi (1994). 

IPG from rat (IPG) or from Lathyrus sativus (LsIPG) showed similar proliferative effects on organotype cultures of cochleovestibular ganglion (CVG). Proliferation levels were estimated by the measurement of PCNA, a nuclear protein essential for DNA synthesis. The numbers below each photomicrograph represent CVG volume size (arbitral units). Scale bar, 100 pm. Reprinted with permission from Ref. [59] Mot. Med., 2003. 

C5H8N2O5, Mr 176.13. Potent neurotoxin in the seeds of Lathyrus sativus as well as other L, Crotalaria, and Acacia species (Fabaceae). The biosynthesis proceeds through L-2,3-diaminopropanoic acid which presumably originates from Asn and is acylated by oxa-lyi-CoA . 

If our present attempt to develop transgenic Lathyrus sativus wilh neurotozin-degrading gene expression is successful, it will be of great help to the farmers of not only India but also to those from other arid regions of the world. 

Lathyrus and Vida are closely related genera of the Faba-ceae both are of considerable economic importance. Although the seeds of some species such as Vida faba and V. sativa, are edible, those of many species of both genera are poisonous. Consumption of seeds of the genus Lathyrus (Fa-baceae) by man and many of his domestic animals produces a syndrome called lathyrism, which may be subdivided into neurolathyrism and osteolathyrism. The most important species that cause neurolathyrism are Lathyrus sativus, L. sylv-estris, L. cicera, L. latifolius, and L. clymenum (Rosenthal,... 

N -Oxalyl-L-2,3-diaminopropionic acid (57) is derived from 2,3-diaminopropionic acid (69), which, in turn, is derived from asparagine (64) (Fig. 13.13), The oxalyl derivative (57) is a potent neurotoxin found in Lathyrus sativus and certain other legumes. The corresponding. /V -methyl derivative occurs in certain cycads such as Cycas drdnalis (Rosenthal, 1991). 

The enzyme catalyzing the formation of homospermidine was identified as a homospermidine synthase [26], an enzyme previously described from two bacterial sources [27,28] and seedlings of Lathyrus sativus [29]. None of these species produces PAs. One of the bacterial enzymes [28] has been purified. Bacterial homospermidine synthase was suggested to catalyze the following reaction ... 

Korus J, Witczak M, Juszczak L, Ziobro R. Grass pea (Lathyrus sativus L.) starch as an alternative for cereal starches rheological properties and retrogradation susceptibility. J Food Eng 2008 88 528-534. 

A problem with the pulses is the presence of various types of toxin, some of which are only destroyed by prolonged heat. For example, soya beans contain a trypsin inhibitor. Aflatoxins produced by the mould Aspergillus flavus, which may contaminate groundnuts, have been found to damage the liver and cause carcinoma in various species. These substances have restricted the use of groundnuts both for human and animal nutrition. Lathyrism (page 419), which may produce permanent paralysis, results from the consumption of large quantities of the pea. Lathyrus sativus, usually when the main crops have failed. 

XXXVII N -Oxalyl-diaminopropionic acid vetchling Lathyrus sativus Fabaceae... 

---