Laser coupling chromatography with

Q. Zhan, A. Gusev, and D. M. Hercules, A novel interface for on-line coupling of liquid capillary chromatography with matrix-assisted laser desorption/ionization detection, Rapid Commun. Mass Spectrom., 13 (1999) 2278-2283. 

V. B. Ivleva, Y. N. Elkin, B. A. Budnik, S. C. Moyer, P. B. O Connor, and C. E. Costello, Coupling thin-layer chromatography with vibrational cooling matrix-assisted laser desorption/ ionization Fourier transform mass spectrometry for the analysis of ganglioside mixtures, Anal Chem., 76 (2004) 6484-6491. 

In addition, for speciation coupling of flow injection analysis and column chromatography with flame AAS and also a direct coupling of HPLC with flame AAS, as is possible with high-pressure nebulization, are most powerful. Here the Cr line in the visible region can be used, which makes the application of diode laser atomic absorption spectrometry possible [325]. This has been shown recently by the example of the determination of methylcyclopentadienyl manganese tricarbonyl. 

Peng, S., Edler, M., Ahhnann, N., Hoffmann, T., Franzke, J. (2005) A new interface to couple thin-layer chromatography with laser desorption/atmospheric pressure chemical ionization mass spectrometry for plate scanning. Rapid Communications in Mass Spectrometry RCM, 19, 2789-2793. 

Lafleur, J.P., Salin, E.D. (2008) Speciation of chromium by high-performance thin-layer chromatography with direct determination by laser ablation inductively coupled plasma mass spectrometry. Ana/yhca/ Chemistry, 80, 6821-6823. 

Qureshi, M.N., Stecher, G., Huck, C., and Bonn, G.K. 2010. Online coupling of thin layer chromatography with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Synthesis and application of a new material for the identification of carbohydrates by thin layer chromatography/matrix free material enhanced laser desorption/ ionization mass spectrometry. Rapid Commun. Mass Spectrom., 24 2759-2764. 

Figure 6.6. TWo methods of direct coupling of chromatography with laser desorption/ionization. (A) direct coupling HPLC effluent at atmospheric using a wheeL (B) In vacuo coupling of capillary electrophoresis using a tape. (Figures reproduced from Refs. 77 and 78, with permission.)...

Karuna, R. and Sashidhar, R. B., Use of ion-exchange chromatography coupled with TLC-laser scanning densitometry for the quantitation of fumonisin Bl,... 

Mao, Y., Zhang, X.M. (2003). Comprehensive two-dimensional separation system hy coupling capillary reverse-phase liquid chromatography to capillary isoelectric focusing for peptide and protein mapping with laser-induced fluorescence detection. Electrophoresis 24, 3289-3295. 

Microdialysis is a sampling technique that must be coupled with an analytical method to identify and quantify chemical components of the dialysate. The samples can be analyzed immediately upon collection (i.e., online), or they can be stored (—80°C) for future analysis. Only analytical techniques sensitive enough to measure both small sample volumes and low concentrations of substances can be used to measure compounds in dialysate samples. High-performance liquid chromatography (HPLC) or capillary electrophoresis (CE) combined with ultraviolet (UV), electrochemical (EC), or laser-induced fluorescence (LIF)... 

Li C, Hong Y, Tan YX et al. Accurate qualitative and quantitative proteomic analysis of clinical hepatocellular carcinoma using laser capture microdissection coupled with isotope-coded affinity tag and two-dimensional liquid chromatography mass spectrometry. Mo/ Cell Proteomics 2004,3399-409. 

Because the chapter is about DOM, detailed information about the role of colloids and the analytical techniques are given elsewhere (e.g., Buffle and Leppard, 1995 Kretzschmar et al., 1999 Frimmel et al., 2007). Different separation techniques, like ultrafiltration, size exclusion chromatography, and flow field-flow fractionation can be coupled with UV-vis absorption and ICP-MS to show the interaction of metals and colloids. Elements like Ni, Cu, Cr, and Co are associated mainly with smaller-size DOM fractions whereas Al, Fe, lanthanides, Sn, and Th are associated with larger-size DOM fractions (Bolea et al., 2006). The laser-induced breakdown detection (LIBD) is a new, sensitive method for the quantification of aquatic colloids of lower-range nanometer size in very low concentration, which cannot be... 

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