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Matrix-assisted laser coupling with liquid chromatography

Q. Zhan, A. Gusev, and D. M. Hercules, A novel interface for on-line coupling of liquid capillary chromatography with matrix-assisted laser desorption/ionization detection, Rapid Commun. Mass Spectrom., 13 (1999) 2278-2283. [Pg.133]

Strege summarized the technique of high-performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-ESI-MS) in dereplication of natural products. In contrast to earlier electron impact ionization (El), ESI technique is applicable to virtually any ion in solution with a soft ionization process. A comparison of ESI with fast atom bombardment (FAB), matrix assisted laser desorption ionization (MALDI), atmospheric pressure chemical ionization (APCI) and other techniques demonstrates its superior sensitivity, compatibility and reliability when coupled with HPLC [51]. [Pg.659]


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See also in sourсe #XX -- [ Pg.117 , Pg.118 , Pg.119 ]




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Coupled chromatography

Laser assisted

Laser coupling chromatography with

Laser liquid chromatography

Lasers liquids

Liquid chromatography coupled with

Liquid chromatography coupling

Liquid matrix

Matrix assisted

Matrix-assisted laser

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