Lactose alpha

Liakatos, A. Kiefel, M. J. yon Itzsteirr, M., Synthesis of lactose-based S-linked sialylmimetics of alpha(2,3)-sialosides. Org. Lett. 2003,5,4365-4368. 

Wagner KG, Dressier JA. A corn starch/alpha-lactose monohydrate compound as a directly compressible excipient. Pharm Technol (Europe) March 2003. 

Lactose may be obtained in two crystalline forms a-lactose and P-lactose (in addition to amorphous forms). The alpha form is obtained when water is incorporated into the lattice structure during crystallization (usually by supersaturation below 93.5°C) (5). Alternatively, the beta form does not contain water and exists as a non-hygroscopic and anhydrous form. Amorphous lactose is formed when either the crystallization is rapid or sufficient transient energy is introduced into the crystalline forms (74), i.e., spray drying (75), micronization and milling (76), freeze-drying, and anti-solvent crystallization (77). 

Nickerson, T. A. and Moore, E. E. 1974A. Alpha lactose and crystallization rate. J. Dairy Sci. 57, 160-164. 

Olano, 0. and Rios, J. J. 1978. Treatment of lactose with alkaline methanolic solutions Production of beta-lactose from alpha-lactose hydrate. J. Dairy Sci. 61, 300-302. 

Troy, H. C. and Sharp, P. F. 1930. Alpha and beta lactose in some milk products. J. Dairy Sci. 13, 140-157. 

Catapres Clonidine HC1 USP 0.1, 0.2, 0.3 mg Tablet Hypertension Alpha-adrenoreceptor agonist Colloidal silicon dioxide, corn starch, dibasic calcium phosphate, gelatin, glycerin, lactose, magnesium stearate, methylparaben, propylparaben Boehriner Ingelheim (Mylan)... 

Starlac —a spray-dried compound consisting of 85% alpha-lactose monohydrate and 15% maize starch ... 

Ludipress —an excipient consisting of 93% alpha-lactose monohydrate, 3.5% povidone, and 3.5% crospovidone ... 

Ludipress LCE—an excipient consisting of 96.5% alpha-lactose monohydrate and 3.5% povidone ... 

Ticehurst MD, et al. 1996. Characterisation of the surface properties of alpha-lactose monohydrate with inverse gas chromatography, used to detect batch variation. Int. J. Pharm. 141 93-99. 

Amorphous or glassy lactose is formed when lactose-containing solutions are dried quickly. The dry lactose is noncrystalline and contains the same ratio of alpha/beta as the... 

C12H19NO 4-(hexyloxy)aniline 39905-57-2 25.00 0.9631 2 24891 C12H24012 alpha-lactose monohydrate 5989-81-1 20.00 1.5470 1... 

Alpha lactose monohydrate Inexpensive, relatively inert most widely used often used with Avicel PH MCC to improve disintegration... 

Lerk CF, Andreae AC, de Boer AH, et al. Increased binding capacity and flowability of alpha-lactose monohydrate after dehydration. / Pharm Pharmacol 1983 35(11) 747-748. 

Amine and Hegsted (1971) obtained similar carbohydrate effects studying iron absorption. Glucose is the most commonly used source of dietary carbohydrate in semipurified diets. Pennell et al. (1976) reported that beta-lactose in place of sucrose reduced the relative biological value of iron as sodium iron pyrophosphate when fed to rats. However, alpha-lactose or glucose in place of the sucrose did not affect the bioavailability of this iron source. Similarly, the source of fat can affect the bioavailability of dietary iron but, the level of dietary fat has no effect (Mahoney et al., 1980). 

Lactose (98% of purity) was supplied from Fluka, octa-O-acetyl-lactose was synthesized for the purpose of this paper[ ]. The chemical structures of both investigated saccharides are presented in Fig 1. In order to avoid caramellization of lactose (this disaccharide caramelizes relatively easy) the sample was heated very quickly to its melting point and when whole sample was molten it was supercooled very quickly. Isobaric dielectric measurements at ambient pressure were carried out using a Novo-Control GMBH Alpha dielectric spectrometer (10 -10 Hz). The samples were placed between two stainless steel flat electrodes of the capacitor with gap 0.1 mm. The temperature was controlled by the Novo-Control Quattro system, with use a nitrogen-gas cryostat. Temperature stability of the samples was better than 0.1 K... 

Ferretti A. and Flanagan V.P. (1973) Characterization of volatile constituents of an V-alpha-formyl-i-lysinc-D-lactose browning system. J. Agric. Food Chem. 21, 35-7. 

Lactose (LAK-tose) is a white, odorless, sweet-tasting solid commonly known as milk sugar because it occurs in the milk of many animals, primarily the mammals. The lactose content of milk ranges from about 2 to 8 percent in cows and 5 to 8 percent in human milk. Lactose occurs in two isomeric forms, a-lactose and P-lactose, with the latter somewhat sweeter than the former. The alpha form tends to occur as the monohydrate,... 

Alpha lactose is found in cow s milk and beta lactose in human milk. During pasteurization of cow s milk, the alpha isomer is converted into the beta isomer. 

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