Lab-on-Chip Devices for Separation-Based Detection

Lab-on-Chip devices for separation-based detection refer to Lab-on-Chip devices that are capable of performing detection based on the result of separation. Both separation and detection functionalities should be integrated in a single chip. 

Lab-on-Chip Devices for Separation-Based Detection, Fig. 1 A typical mimicapillaiy elecbophoresis system with straight capillary separation channel (7) buffer reservoir, (2) sample reservoir, (5) sample waste reservoir, (4) end waste reservoir, (5) buffer injection channel, (6) sample injectirai channel, (7) capillary separation chaimel, (8) injection cross point... 

There are many good review papers discussing Lab-on-Chip devices for separation-based detection [5,6]. Only four representative examples are selected to illustrate separation and detection principles and to identify challenges in this rapidly emerging research area. 

Lab-on-Chip Devices for Separation-Based Detection, Fig. 2 Photomicrograph of the central part of a microchip incorporating DEP positioning and EC detection, showing the central Ag reference electrode and two sets of ISFET and DEP microelectrodes [7]... 

Lab-on-Chip Devices for Separation-Based Detection, Rgure 2... 

Lab-on-ChIp Devices for Separation-Based Detection, Rgure 5 Geometry ovenriew and optical setup of a microchip incorporating CE separation and fluorescence detection [10]... 

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