L - Butane

Reactions of /l-Butane. The most important industrial reactions of / -butane are vapor-phase oxidation to form maleic anhydride (qv), thermal cracking to produce ethylene (qv), Hquid-phase oxidation to produce acetic acid (qv) and oxygenated by-products, and isomerization to form isobutane. 

V-Nitrosomethylamino)-4-(3-pyridyl)-l-butanal 4-(V-Nitrosomethylamino)-l-(3-pyridyl)-l-butanone Af-Nitrosomethylethylamine... 

Di- and polysubstituted pyrrolizines are uncommon. The only pyrrolizine isolated from the intramolecular aldol condensation of 2-acetyl-l-(butan-3-on-l-yl)pyrrole was the 6,7-disubstituted compound 223.122 A small amount of the 5,6-disubstituted pyrrolizine (145d) was obtained when the 2-formylpyr-ryl anion was condensed with l,2-di(phenylsulfonyl)ethene.90 By contrast with the production of the single isomer (223), the homologous diketone 224... 

Trans -2-butenyl-l- 3-Methyl-l-butane-thioacetate thiol... 

SYNS 4-CHLORBUTAN-l-OL (GERMAN) 4-CHLORO-l-BUTANE-OL 4-CHLOROBUTANOL TETRAMETHYLENE CHLOROHYDRIN... 

SYNS BUTANECARBOXYI.IC ACID l-BUTANE-CARBOXYLIC ACID FEMA No. 3101 PENTANOIC ACID n-PENTANOIC ACID PROPYLACETIC ACID VALERIANIC ACID n-VALERIC ACID... 

CHLOROBUTANE pOT) see BQQ750 4-CHLORO-l-BUTANE-OL see CEU500 CHLOROBUTANOL see ABDOOO 4-CHLOROBUTANOL see CEU500... 

Hydrolysis to Nonproteinogenic Amino Acids. Numerous amino acids, including a-branched ones, have been prepared from Boc-BMI. Only a few examples can be alluded to here (11) from (5)-(l), EtI, and Br(CH2)4Cl (12) from (5)-(l), 3-methylbutanoyl chloride, and Lithium Triethylborohydride (13) from (R)-(l), butanal, and dibutylcuprate (14) from (S)-(l) and 4-phenylbut-2-enoate. ... 

Resolution 3t3-Acetoxy-A. etienic add. T-Acid from a tetranitrofluorenone and an optically active hydroxylamine. i><—>Butane-2,3-diol. L.(+)-Butane-2,3-dithiol. (By crystallization Silver acetate). 10-Camphorsulfonic acid. 10-Camphorsulfonyl chloride. 4-(4-Carboxy-phenyl) semicarbazide. Complex from ethylene, platinous chloride, and (- -)-l-phenyi-2-aminopropane. Debydroataetylamine. Diisopinocampheylborane. Di-p-toluoyl-o-tartrate. d- and /-u-Phenylethylamiiie. L-Pyrrolidonecarboxylic add. a-(2,4,S,7-Tetianitro-9-fluorenyl-ideneaminooxy)-propionic acids. 

Bacillus sp. torynebacterium sp. ACTINOMYCETES granary 3-Methyl-l-butanal, 2-Methyl-2-hydroxy-3-keto butanal, pyrazines... 

Reaction with the halogens breaks the bridgehead bond and leads to 1,3-dihalobicyclo[l.l.l]butanes. When halide salts are included, mixed dihalides are formed, suggesting an ionic mechanism. " ... 

Hecht et al. (1563, 1565) suggested that nicotine was the precursor of NNK and 4-(iV-methylnitrosamino)-4-(3-pyridinyl)-l-butanal in tobacco via opening of the pyrrolidine ring of nicotine. 

It is unlikely that nicotine itself contributes to exposure to nitroso compounds [A -nitrosonomicotine (NNN), 4-(A-methylnitrosamino)-4-(3-pyridinyl)-l-butanal, and 4-(A-methylnitrosamino)-l-(3-pyridinyl)-l-butanone (NNK)] due to chemically mediated intragastric nitrosation. 

Alcohol 45 was synthesized by treatment of 4-benzyloxy-l-butane oxide 44 with sodium benzyloxide, then converted to the acetoxymethyl ether 46, which condensed with diacetylguanine to give 47, whose deprotection gave 48 (86JMC1384). It is less active than DHPG against HSV-1. 

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