Kunkel

Thiel, B.L., Kunkel, D.D., Viney, C. Physical and chemical microstructure of spider dragline a study by analytical transmission electron microscopy. Biopolymers 34 1089-1097, 1994. 

The user s manual is Ille (1978). Other references are Mackay (1973), Kunkel (1983), Schmidt (1959), and Bird, (1966). 

Kunkel, E. J., Plavec, L, Nguyen, D., Melrose, J., Rosier, E. S., Kao, L. T., Wang, Y., Hytopoulos, E., Bishop, A. C., Bateman, R., et al. (2004). Rapid structure-activity and selectivity analysis of kinase inhibitors by Bio Map analysis in complex human primary cell-based models. ASSAY Drug Dev. Technol. 2 431-441. 

Kunkel, Ed, "Plasma Physics in Theory and Application , McGraw Hill, NY (1966) 14) G. 

In Table 16 particular problems and analytical processes are summarized. The literature quoted in the table makes quick access to this subject possible for the reader. A general and detailed overview of the analysis of surfactants can, for example, be found in books of Longman [192], Cross [193], and Schmitt [194], as well as in the reviews of Raid [195,196] and Kunkel [197-199]. In the area of analysis of surfactants present in trace quantities and for metabolites the book by Swisher can be put to good use [200]. 

Hoffrnan, E.P., Kunkel, L.M. (1989). Dystrophin abnormalities in Duchenne/Becker muscular dystrophy. Neuron 2, 1019-1029. 

Butcher EC, Berg EL, Kunkel EJ. Systems biology in drug discovery. Nat Bio-technol 2004 22 1253-9. 

Carrots (Boleo) were peeled by 2% NaOH at 88-96°C for 4 minutes, minced by a meat mincer (2 mm) and homogenised for 2 minutes by an ULTRA-TURRAX T25 homogenizer (from Jahne Kunkel). The carrot mash was preheated to 45°C (20 minutes) before the enzyme preparations, 25 mg enzyme protein/kg mash, were added. The enzymes were dissolved in water to give a dilution of 5% (v/v) of the carrot mash. The mash was incubated at 45°C under stirring (60 rpm) for 2 hours, before the enzymes were inactivated at 86°C for 5 minutes in a microwave oven. Finally the purees were homogenised for 1 minute by ULTRA TURRAX. The viscosity of the puree was measured by a BROOKFIELD viscosimeter Model DV-n + with spindle A from HELIPATH SPINDLE SET at 2.5 rpm thermosta-ted at 50°C. The stability of the puree was measured as the sediment (in %) after centrifugation in 10 ml tube a 1660 x g for 10 minutes. 

Acid-catalysed rearrangement of epoxides is another widely used reaction in the fine chemicals industry. Here again the use of solid acid catalysts such as zeolites is proving advantageous. Two examples are shown in Fig. 2.25 the isomerization of rsophorone oxide (Elings et al., 1997) and the conversion of a-pinene oxide to campholenic aldehyde (Holderich et al., 1997 Kunkeler etal., 1998). Both products are fragrance intermediates. 

Ward, P.A., Till, G.O., Kunkel, R. and Beauchamp, C. (1983). Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury. J. Clin. Invest. 72, 789-801. 

High-speed homogenizer, e.g., Ultra-Turrax (Jankeu. Kunkel, Staufen/Br., Germany)... 

Atkins MB, Kunkel L, Sznol M, Rosenberg SA. High-dose recombinant interleukin 2 therapy in patients with metastatic melanoma Long-term survival update. Cancer J Sci Am. 2000 6(suppl 1) SI 1-14. 

Foxman EF, Kunkel EJ, Butcher EC. Integrating conflicting chemotactic signals. The role of memory in leukocyte navigation. J Cell Biol 1999 147(3) 577-588. 

Cheng SS, Lai JJ, Lukacs NW, Kunkel SL. Granulocyte-macrophage colony stimulating factor up-regulates CCR1 in human neutrophils. J Immunol 2001 166 1178-1184. 

Campbell JJ, Murphy KE, Kunkel EJ, et al. CCR7 expression and memory T cell diversity in humans. J Immunol 2001 166 877-884. 

Kim CH, Kunkel EJ, Boisvert J, et al. Bonzo/CXCR6 expression defines type 1-polarized T-cell subsets with extralymphoid tissue homing potential. J Clin Invest 2001 107 595-601. 

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