Ketosis, mild diabetic

Mild diabetic ketosis. If the patient is fully conscious and there has been no nausea or vomiting for at least 12 h, intravenous therapy is unnecessary. It is reasonable to give small doses of insulin s.c. 4-6-hourly and fluids by mouth. 

Ketosis is mild in starvation but severe in diabetes meUitus and ruminant ketosis. 

In moderate metabolic acidosis which occurs in cases of mild renal insufficiency, infant diarrhoea, diabetic ketosis etc. 

On testing, her random blood glucose was f4 mmol/L (3.5-10 mmol/L) and her urine tested negative for ketones. A diagnosis of mild ketosis was made presenting secondary to newly diagnosed type 1 diabetes. 

DKA is the most important and demanding medical emergency within the fields of diabetology and endocrinology. There is no generally accepted definition of DKA and in particular very mild cases may be problematic. As a minimum it seems reasonable to require that pH is below normal range and that levels of ketoacids (ketone bodies) in blood or urine are markedly elevated. As outlined in Table 1 there is a continuous deterioration from clinically insignificant stress ketosis to full blown severe ketoacidosis. In the US population it has been estimated that between 2% and 8% of hospital admissions in children with diabetes are due to DKA [7] and that the annual incidence rate of DKA in children is around 5 per... 

Ketosis— The most common causes of this condition— which is characterized by an excess of ketones in the blood— are (1) diabetes (2) diets high in fat and protein, but low in carbohydrate (3) fevers and (4) starvation. A mild ketosis in normally healthy people is usually not dangerous, unless it occurs regularly over a long period of time, flien, it may lead to such problems as (1) excessive urinary loss of sodium and water (2) acidosis which provokes the loss of calcium from bone, and potassium from muscle and (3) the accumulation of uric acid (a waste product of protein metabolism) in the blood, and sometimes in the soft tissues where it causes damage and pain (the latter disorder is commonly called gout). Uric acid buildup is usually treated with alkalizers to prevent the formation of kidney stones. However, the alkalizers may cause other alterations in mineral metabolism. 

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