Ketone, heptyl phenyl

Ketone dineopentyl-, preparation of, 54, 97 Ketone, heptyl phenyl, 53, 78 Ketones, alkylation of, 54, 48 Clemmensen reduction of, 53,... 

Ketone, aralkyl, selective a-bromina-tion of,53, 111 Ketone, heptyl phenyl, 53,78 Ketones, preparation using 1,3-dithiane, 50,74 51,80... 

KETONE, HEPTYL 4-PYRlDYL see HBF600 KETONE, a-HYDROXY BENZYL PHENYL see BCP250 KETONE, 7-(2-HYDROXY-3-... 

A range of different functional groups has been introduced into the V-position of the C3 side chain, as shown in Table 6.10. A number of different functionalities were shown to be tolerated in this position, with lipophilic groups such as methyl and dithiolane being preferred over polar groups such as ketones and alcohols. Ketone (118) had similar CBi receptor affinity to the unfunctionalised -heptyl compound (84), while alcohol (120) had lower affinity. The phenyl ketone (119) had lower CBi receptor affinity than the simple benzyl-substituted compound (116), but higher CB2 affinity, with about 12-fold selectivity for CB2 over CBi. 

KETONES AND ALCOHOLS FROM ORGANOBORANES 1. PHENYL HEPTYL KETONE 2. 1-HEXANOL ... 

The resulting mixture is saturated with sodium chloride, and the organic phase is separated and washed with three 50-ml. portions of saturated brine solution. The organic solution is dried over sodium sulfate and concentrated on a rotary evaporator. Distillation of the residue through a 7-cm. Vigreux column separates 15.34-15,99 g. (75-80%) of phenyl heptyl ketone, b.p. 118-120° (0.60 mm.) n2eD 1.5034 (Note 9). 

Phenyl heptyl ketone has been prepared by the Friedel-Crafts acylation of benzene with octanoyl chloride.6 It is also a product of the thermal decomposition of the mixed ferrous salts of benzoic and octanoic acids.7... 

The present preparation of phenyl heptyl ketone illustrates... 

KETONES AND ALCOHOLS FROM ORGANOBORANES 1. PHENYL HEPTYL KETONE 2. HEX-ANOL 3. 1-OCTANOL,53, 77 Ketones, Clemmensen reduction of, 53, 89... 

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