Kandel, Eric

Eric R. Kandel, a professor at Columbia University, is one of the world leaders in the science of the central nervous system, which he prefers to call the science of mind. A winner of the Nobel Prize in Medicine or Physiology in 2000, together with Arvid Carlsson and Paul Greengard, for his studies on the mechanism of learning, he has written the history of his life in science in an elegant book In Search of Memory. In this book, Kandel defines five principles of the science of mind. Here they are (and I quote directly) ... 

Kupfermann, Irving. 1991. "Hypothalamus and Limbic System Peptidergic Neurons, Homeostasis, and Emotional Behavior." In Principles of Neural Science, edited by Eric R- Kandel, James H. Schwartz, and Thomas M. Jessell. 3d ed. New York Elsevier. 

Eric R. Kandel Physiology/Medicine Molecular basis of learning... 

Dopamine receptor (Dl-R, D2-R) Arvid Carlsson (Sweden, D 5HT signalling), Paul Greengaard (USA, D signalling) Eric Kandel (Austria/USA, 5HT memory) (Nobel Prize, Physiology/ Medicine, 2000) 5.4... 

Arvid Carlsson Paul Greengard Eric R. Kandel... 

It was named Dopamine because it was a monoamine, and its synthetic precursor was 3,4-dihydroxyphenylalanine (L-DOPA). He was awarded Nobel Prize in 2000 along with Eric Kandel and Paul Greengard in Medicine for showing that dopamine is not just a precursor of noradrenaline and adrenaline, but also neurotransmitter as well. DO is a type of neurotransmitter naturally produced in by the human body. It is also a neurohormone released by the hypothalamus. It is a chemical messenger that is similar to adrenaline and affects the brain processes that control movement, emotional response, and the capacity to feel pleasure and pain. It is vital for performing balanced and controlled movements [172,173], In the extra-cellular fluid of the central nervous system, the basal DO concentration is very low (0.01-1 pM). Abnormal levels of DO have been linked with Parkinson s disease, Tourette s syndrome, Schizophrenia, attention deficit hyperactive disorder and generation of pituitary tumours [174-176],... 

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