Juvenile hormone analogues

Homogeraniol is an important intermediate in syntheses of squalene, aplyslstatin,8 dendrolasin,9 and juvenile hormone analogues.18 The present procedure affords an efficient, stereoselective method for preparing (E)-homogeraniol, contaminated by at most 1-2% of the Z isomer. 

Rondot I., Quennedey B., Courrent A., Lemoine A. and Delachambre J. (1996) Cloning and sequencing of a cDNA encoding a larval-pupal-specific cuticular protein in Tenebrio molitor (Insecta, Coleoptera). Developmental expression and effect of a juvenile hormone analogue. Eur. J. Biochem. 235, 138-143. 

Mundall E. C., Szibbo C. M. and Tobe S. S. (1983) Vitellogenin induced in adult male Diploptera punctata by juvenile hormone and juvenile hormone analogue identification and quantitative aspects. J. Insect Physiol. 29, 201-207. 

There has been some work suggesting that some synergists, including PBO, may have morphogenic effects similar to juvenile hormone analogues (Bowers. 1968), This has not been substantiated (Red fern et at.. 1969) and it is most likely thaL Lite effect is due to mixed function oxidase inhibition interfering with the terminal steps in juvenile hormone synthesis (Staai. 1986). 

With a number of juvenile hormone analogues it could be shown that the concept of insect control by interaction with their hormone system is valid (28, 29). In view of the slow progress with compounds affecting the hormone system of ecdysteroids (30) the introduction of brassinosteroids may give some new impetus to the search for ecdysteroid-based insect growth regulators. 

Edwards, J.P., Short, J.E. and Abraham, L. (1991) Large-scale evaluation of the insect juvenile hormone analogue fenoxycarb as a long-term protectant of stored wheat. Journal of Stored Products Research 27, 31-39. 

El-Guindy, M.A., El-Rafai A.R.M. and Abdel-Sattar, M.M. (1982) The pattern of crossresistance to insecticides and juvenile hormone analogues in a diflubenzuron-resistant strain of the cotton leaf worm Spodoptera littoralis Boisd. Pesticide Science 14, 235-245. 

Effective doses of these derivatives against Pyrrhocoris apterus and Dysdercus cingulatus are 51 0.5,52 0.01,53 0.000 04,54 0.000 01 and 55 0,000 002 pg/insect. The latter derivative is the most potent juvenile hormone analogue known so far. Only the isomers of S-configuration of this type are active, while those containing... 

Recent studies have shown that the insect juvenile hormone analogues juvabione (87) and derivatives (88)—(90), produced by Abies alba, occur in 4R,VR and 4R,1 S diastereomeric forms. It has been suggested that these sesquiterpenoids (c/. Vol. 8, p. 67) may be of value in chemosystematic studies of... 

Pheromones.—Further use has been made of Bestmann s unitized construction principle to synthesize a variety of 1,5- and 1,6-alkadiene pheromones. Standard Wittig methods have been used to synthesize (3Z,6Z,9Z)-1,3,6,9-nonadecatetraene (142) (Scheme 19) (now identified as a sex pheromone of the winter moth O. brumata), sex attractants (143) of Lasiocampidae species, and the trail pheromone (144) of Pharaoh s ant. A variety of 2,4-dienoic ester insect juvenile hormone analogues (145) with terminal cyclohexene, cyclohexane, or pinene rings have been prepared by phosphonate olefination. The queen... 

Webster, R.P., and R.T. Carde The Effects of Mating, Exogenous Juvenile Hormone and a Juvenile Hormone Analogue on Pheromone Titre, Calling and Oviposi-tion in the Omnivorous Leafroller Moth. Platynota stultana). J. Insect Physiol. 30, 113-118(1984). 

Robinson, G.E. Effects of a Juvenile Hormone Analogue on Honey Bee Foraging Behaviour and Alarm Pheromone Production. J. Insect Physiol. 31, 277-282 (1985). 

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