Joint Meeting of Experts on Pesticides Residues

The WHO/FAO Joint Meeting of Experts on Pesticide Residues (JMPR) has given recommendations on interpretation of cholinesterase inhibition (FAO 1998, 1999), see Section 4.7.7.3.1. 

In 1961, the Joint FAO/WHO Expert Committee on Food Additives (JECFA) and the Joint Meeting of Experts on Pesticides Residues (JMPR) adopted this approach in a slightly modified form The safe level was called the Acceptable Daily Intake (ADI) and expressed in mg/kg body weight per day (Vermeire et al. 1999, ECETOC 2003). Usually, a safety factor of 100 is used by JECFA and JMPR for establishing ADIs by this ADI approach however, the procedures adopted by JECFA and JMPR do not generate a clear justification for deviation from the factor of 100, but in some individual cases, an expert explanation is given for the use of factors other than 100 (Vermeire et al. 1999). 

FAOAVHO. 1976. Pesticide residues in food. Report of the 1975 Joint Meeting of the FAO Working Party of Experts on Pesticides Residues and the WHO Expert Committee on Pesticide Residues. Geneva, Switzerland Food and Agricultural Orgaiuzafion of the United Nations and World Health Organization. FAO Plant Production and Protection Series no. 1, WHO Technical Report Series no. 592. 

FAO/WHO. 1991. Pesticide residues in food-Disulfoton. Report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and a WHO Expert Group on Pesticide Residues. Food and Agriculture Organization of the United Nations and the World Health Organization, Rome, Italy. Pp. 151 -172. 

Reports of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the WHO Core Assessment Group (2003) and (2000)... 

FAO and WHO followed in 1961 and 1963". Since 1965 they have been held annually. Each session is formally entitled a Joint Meeting of the FAO Panel of Experts on Pesticide Residues and the Environment with the WHO Expert Committee (or Panel) on Pesticide Residues but they are more usually referred to as FAO/WHO Joint Meetings on Pesticide Residues (JMPR). 

As this paper is primarily concerned with the activities of Joint Meetings of Experts (JMPR), it seems sufficient to record that since 1966 the CCPR has held ten sessions of intergovernmental discussions aiming at common limits for residues of pesticides in food commodities. They have been based on the recommendations of Joint FAO/WHO Meetings of Experts which have been used throughout this time as an independent international source of scientific advice relating to the occurrence of residues of pesticides in food. 

So far, metabolic studies of about 30 synthetic pyrethroids, including their chiral and geometrical isomers, have been carried out in mammals [1], However, detailed metabolism data have not necessarily all been published in scientific journals. In some cases, the reports of joint World Health Organization-Food and Agricultural Organization (WHO/FAO) expert meetings on pesticide residues and the... 

Toxicological evaluations of food additives and of contaminants, naturally occurring toxicants and residues of veterinary drugs in food produced by the Joint FAO/WHO Expert Committee on Food Additives (JECFA), and of pesticide residues in food by the Joint FAO/WHO Meeting on Pesticide Residues (JMPR) are used by the Codex Alimentarius Commission and national governments to set international food standards and safe levels for protection of the consumer. 

FIGURE 3.4 Examples of monographs from the Joint FAO/WHO Expert Committee on Food Additives (JECFA) and from the Joint FAO/WHO Meeting on Pesticide Residues (JMPR) published by the WHO. 

---