Japanese flounder

Hirono, I., B.H. Nam, T. Kurobe and T. Aoki. Molecular cloning, characterization, and expression of TNF cDNA and gene from Japanese flounder Paralychthys olivaceus. J. Immunol. 165 4423—4427, 2000. 

De Jesus, E.G., T. Hirano and Y. Inui. Changes in cortisol and thyroid hormone concentrations during early development and metamorphosis in the Japanese flounder, Paralichthys olivaceus. Gen. Comp. Endocrinol. 82 369-376, 1991. 

Tokuda, Y., K. Touhata, M. Kinoshita, H. Toyohara, M. Sakaguchi, Y. Yokoyama, T. Ichikawa and S. Yamashita. Sequence and expression of a cDNA encoding Japanese flounder glucocorticoid receptor. 

Takeuchi, T., J. Dedi, Y. Haga, T. Seikai and T. Watanabe. Effect of vitamin A compounds on bone deformity in larval Japanese flounder (Paralichthys olivaceus). Aquaculture 169 155-165, 1998. 

Chitosan Microsphere Plasmid DNA Japanese flounder Oral... 

Tian, J., Yu, J., and Sun, X. 2008. Vet Chitosan microspheres as candidate plasmid vaccine carrier for oral immunisation of Japanese flounder (Paralichthys olivaceus). Immunol. Immunopathol. 126 220-229. 

FURUTTA H, TANAKA H, YAMAMOTO T, SHIRAJSHI M and TAKEUCHI T (2001) Effects of high dose of vitamin A on reprodnction and egg quahty of Japanese flounder Paralichthys olivaceus Fisheries Science, vol. 67, pp. 606-613. 

FURUTTA H, TANAKA H, YAMAMOTO T, SUZUKI N, TAKEUCHI T (2003) Supplemental effect of vitamin A in diet on the reproductive performance and egg quahty of the Japanese flounder Paralichthys olivaceus (T S), Aquaculture Research, vol. 34, pp. 461-468. 

GATESOUPE F J, ARAKAWA T and WATANABE T (1989) The effect of bacterial additives on the production rate and dietary value of rotifers as food for Japanese flounder, Paralichthys olivaceus. Aquaculture 83 39—44. 

HIRONO l, TAKAMI M, MIYATA M, MIYAZAKI T, HAN HJ, TAKANO T, ENDO M, AOKI T (2004), Characterization of gene structure and expression of two toll-like receptors from Japanese flounder, Paralichthys olivaceus , Immunogenetics, 56,38-46. 

KONDO H, YEU TZEH AG, mRONO I, AOKi T (2007), Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus . Fish Shellfish Immunol, 23, 1089-94. 

ATCC 15947 was used by i.p. injection with a booster at 3 weeks, leading to complete protection (RPS = 100%) in Japanese flounder. Some success resulted from oral application for 5 days (RPS = 56%) when the antigens were incorporated into alginate microspheres (Cheng et al., 2010b). 

HU, Y.-H. and SUN, l. (2011) A bivalent Vibrio harveyi DNA vaccine induces strong protection in Japanese flounder (Paralichthys olivaceus). Vaccine 29,4328-4333. 

YANG, H., CHEN, J., YANG, G., ZHANG, X.H., LIU, R. and xuE, X. (2009) Protection of Japanese flounder Paralichthys olivaceus) against Vibrio anguiUarum with a DNA vaccine containing the mutated zinc-metalloprotease gene. Vaccine 27, 2150-2155. 

Recently, an aluminium hydroxide-adjuvanted E. tarda vaccine was prepared and injected i.p in Japanese flounder. The resultant protection was found give an RPS of 69% (Jiao et al. 2010a). Immunisation with the antigen alone gave an RPS of 34%, so in this system alum seemed to be a promising adjuvant. However, when FIA was used an RPS of 81% was seen, thus showing that the oil adjuvant would be a more promising line of research. 

ASHiDA T, OKiMASu E, ui M, HEGURi M, OYAMA Y, AMEMURA A. Protection of Japanese flounder Paralichthys olivaceus against experimental edwardsieUosis by formalin-killed Edwardsiella tarda in combination with oral administration of immunostimulants. Fisheries Science 1999,65,527-530. 

CAIPANG CM, HIRONO I, AOKi T. Induction of antiviral state in fish cells by Japanese flounder, Paralichthys olivaceus, interferon regulatory factor-1. Fish Shellfish Immunol 2005,19,79-91. 

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