IV-glycan

Ramirez-Soto, D. and Poretz, R.D. (1991) The (l-3)-linked (X-L-fucosyl group of the IV-glycans of the Wistaria floribunda lectins is recognised by a rabbit antiserum. Carbohydate Research 213, 27-36. 

Reason, A.J., Ellis, L.A., Appleton, J.A., Wisnewski, N., Grieve, R.B., McNeil, M., Wassom, D.L., Morris, H.R. and Dell, A. (1994) Novel tyvelose-containing tri- and tetra-antennary IV-glycans in the immunodominant antigens of the intracellular parasite Trichinella spiralis. Glycobiology 4, 593-603. 

K. Karaveg, A. Siriwardena, W. Tempel, Z.-J. Liu, J. Glushka, B.-C. Wang, and K. W. Moremen, Mechanism of class 1 (glycosylhydrolase family 47) a-mannosidases involved in iV-glycan processing and endoplasmatic reticulum quality control,./. Biol. Chem., 280 (2005) 16197-16207. 

Fig. 2. iV-glycans of the hybrid type. A triantennary structure with sialylated Af-acetyllactosamine (LacNAc) building blocks B biantennary structure with sialylated or fucosylated poly-LacNAc building blocks. The N-glycan core structure is written in bold letters... 

Y. Kita, Y. Miura, J.-i. Furukawa, M. Nakano, Y. Shinohara, M. Ohno, A. Takimoto, and S.-I. Nishimura, Quantitative glycomics of human whole serum glycoproteins based on the standardized protocol for liberating IV-glycans, Mol. Cell. Proteomics, 6 (2007) 1437-1445. 

Examples of the main types of fV-linked oligosaccharides of glycoproteins. The structure within the gray box represents the pentasaccharide core common to all IV-glycans... 

Glycomics Glycopeptides Glycoproteomics Mass spectrometry Nano liquid chromatography iV-glycans 0-glycans Profiling Structural analysis Tandem mass spectrometry... 

ESI-MS/MS is another powerful tool for performing tandem mass spectrometry experiments. To get sequence information on the iV-glycan at m/z 2651 (FucHex7HexNAc4 O Fig. 2), the... 

To complement the glycoproteomics data, the IgG iV-glycans were released, and profiled by MALDI-TOF MS using fhe glycomics strategy described above (O Fig. 10). 

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