Isomers diaminotoluene

Toluidine, nitrotoluene isomers, diaminotoluene, and dinitro-toluene isomers... 

Diaminotoluene isomers CAS Registry Number Melting point. Boiling point. Vapor pressure, kPa (at... 

Diaminotoluene impurities dichlorobenzene, aminotoluene. ni-trotoluene isomers, and dinitrotoluene isomers... 

The studies on catalytic influence of di-aminotoluene isomers on zinc reaction have shown the highest accelerating effect for 3,4-diaminotoluene [82-85]. The difference in catalytic activity of these isomers resulted from the difference in complex formation with Zn(II) ions because the adsorption properties of these isomers on the mercury electrode are similar [82, 84]. Two steps of Zn(II) electroreduction were postulated in the presence of diaminotoluene isomers, with the first electron transfer as a rate-determining step. The influence of diaminotoluene isomers and pH on this electrode process was studied in acetate buffers [86]. 

A novel ECL assay for the determination of 2,4- and 3,4- diaminotoluene (DAT) isomers is based on reaction of these molecules with Au" and Cu +, respectively, in aqueous solution under oxidizing conditions in buffer-containing tripropylamine [72]. Luminescence is observed upon potential ramping from 0 to -1-2.8 V. The nature of the emitting species was not specified, but could involve a charge-transfer excited state of the metal complex with DAT or an oxidized form of DAT. DAT isomers were screened for ECL enhancement against 32 metals the apparent specificity of Au+ for 2,4-DAT and Cu + for 3,4-DAT is believed to be linked to the radii of each ion. This ECL approach could lead to applications in the determination of some aminoaromatics from degradation of explosives (e.g., TNT) as well as detection and quantifiation of various transition metals in water supplies. 

Ion pair RP-HPLC with DA-UVD offers a good alternative for determination of mixtures of PAA which are difficult to resolve by usual RP-HPLC procedures. After optimization as for the pH and anionic component of the isocratic mobile phase, it was opted for phosphate buffer at pH 2.5, containing 5 mM of sodium 1-hexanesulfonate and MeOH in 65 35 volumetric proportion. The method was applied to detection of banned azo dyes, after reduction to PAA, of which the banned ones are denoted by (entries in Table 1 carrying note e). In a study involving 2-, 3- and 4- chloroaniline (lh), 2- (lb) and 4-toluidine (Id), 3-, 4- (2g) and 5-chloro-2-toluidine, 3-, 4- and 5- nitro-2-toluidine (2h), 2,3-, 2,4- (2e) and 2,6-diaminotoluene (2f), 1- (8a) and 2- naphthylamine (9a) under identical conditions, the isomers were well separated from each other, except for 2- and 4-toluidine which had distinct but close retention times with no baseline separation211. 

The reactions of the dihydrochloride salts of 2,4- and 2,6-diaminotoluene with phosgene in toluene or 1,2-dichlorobenzene solutions have been examined at 25-90 C [1923]. With the 2,4-isomer, acylation occurs initially at the 2-position, followed by a slower acylation at the 4-position direct acylation of both NHj groups occurs at equal rates in the... 

Due to the complex reaction mechanism and to the difficulty to identify all reaction products, few studies have been reported in literature on the selective hydrogenation of dinitrocompounds. In previous papers we have investigated the 2,4-DNT hydrogenation over Pd/C catalysts. This reaction is industrially important for the production of 2,4-diaminotoluene (2,4-DAT) which is used in the synthesis of toluenediisocyanate. We have reported that by carrying out the reaction under mild conditions high yields to the corresponding 2,4-nitroarylhydroxylamine isomers can be obtained /3-5/. 

Bermudez E, Tillery D, and Butterworth BE, The effect of 2,4-diaminotoluene and isomers of dinitrotoluene on unscheduled DNA synthesis in primary rat hepatocytes, Environ. Mutagen, 1, 391, 1979. 

Benzenediamine, ar-methyl- Diaminotoluene Diamino-toluene (mixed isomers) EINECS 246-910-3 HSDB 6059 Methylphenylenediamine Phenylenediamine, ar-methyl- RCRA waste number U221 TDA 8020 Toluene-ar,ar -diamine Toluenediamine Tolylenediamine. 

Synonyms/Trade Names Diaminotoluene, Methylphenylene diamine, TDA, Toluenediamine isomers. Tolylenediamine [Note Various isomers of TDA exist] ... 

Toluene diisocyanates are prepared by direct nitration of toluene to give an 80 20 mixture of the 2,4- and 2,6-dinitro derivatives, followed by hydrogenation to the corresponding diaminotoluenes. Under conditions where the 2-nitrotoluene is first separated and further nitrated, a 65 35 mixture of the dinitro compounds and ultimately of the diamines results. The diamine mixtures are treated with phosgene at temperatures up to 140°C and the derived diisocyanate mixture is isolated and purified by distillation. The two (2,4 and 2,6) isomers differ considerably in reactivity (Table 1.1), so the actual ratio of the two components can be quite important. For many purposes the 80 20 mixture is preferred. The preparation route for the production of TDI is detailed in Fig. 1.7a. 

A methanol extract of the polyurethane is applied to a thin-layer chromatography plate and developed with a mixture of chloroform, ethylacetate, ethanol, glacial acetic acid (120 33 20 7 v.v). Fluran spray reagent reveals the two diaminotoluene isomers. The intensity of the spots are evaluated (500 nm excitation 340 nm emission) using a spectrofluorimeter coupled to a thin film scanner and photomultiplier microphotometer. The method is calibrated against standard solutions of the two diaminotoluene isomers. 

Tables 6.1 and 6.2 show that a variety of quinoxalinones 37a-r and 1,2-DABs 5a, d, h are compatible with these reaction conditions, with diverse 2-benzimidazolyl substituted quinoxalines in good yields. The reactions of 3-phenylacetylquinoxalin-2 (17/)-one 37g with 3,4-diaminotoluene 5d, or 4-nitro-1,2-DAB 5h, produce a mixture of two isomers in almost equal amounts (Table 6.2) (Mamedov et al. 2008a Saihna 2009), as evident from the NMR spectra of the crude products.

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