ISOLDE

Martin Giersberg, Isolde Saalbach and Helmut Baumlein... 

Burge, 1999 Fluticasone 1 mg/d (ISOLDE) 36 months n = 990 Decrease in number of exacerbations reduction of symptoms, no effect on FEVi decline Benefit... 

ISOLDE Inhaled Steroids in Chronic Obstructive Lung Disease in Europe EUROSCOP European Respiratory Society Study on Chronic Obstructive Pulmonary Disease BUD = budesonide PRED = prednisolone. 

Burge PS, Calverly PMA, Daniels JE. The acute effect of oral prednisolone in patients with COPD in the ISOLDE trial responders and non-responders . Am J Respir Crit Care Med 1996 153 A126. 

Jarad NA, Wedzicha JA, Burge PS, Calverley PM. An observational study of inhaled corticosteroid withdrawal in stable chronic obstructive pulmonary disease. ISOLDE Study Group. Respir Med 1999 93(3) 161-6. 

Wahl. U., A. Vantomme, G. Langousche, J.G. Correia, L. Peralta and The ISOLDE Collaboration, 2001, Appl. Phys. Lett. 78, 3217. 

REX-ISOLDE Large Synchrotron/1+// EBIS/LINAC TF Europe (CERN)... 

Hyperfine structure measurements using on-line atomic-beam techniques are of great importance in the systematic study of spins and moments of nuclei far from beta-stability. We will discuss the atomic-beam magnetic resonance (ABMR) method, and laser spectroscopy methods based on crossed-beam geometry with a collimated thermal atomic-beam and collinear geometry with a fast atomic-beam. Selected results from the extensive measurements at the ISOLDE facility at CERN will be presented. 

Orsay and Mainz groups constitute a main effort in this direction. Certainly, these experiments profit from the excellent performance of the ISOLDE mass-separator and from the wide range of elements available in high production yields [RAV79, RAV84]. 

The hfs experiments at ISOLDE may be divided into techniques employing atomic-beams and resonance-cells. Here, we will concentrate on the different atomic-beam experiments performed by the groups mentioned above. The present subject has been discussed in some detail in [EKS85], giving e.g. a full reference list on the atomic-beam works at ISOLDE. 

Note The author of this chapter worked with members of the ISOLDE Collaboration, CERN, CH-1211 Geneva 23, Switzerland. 

In this section we will briefly discuss the different atomic-beam methods used in hfs measurements at ISOLDE, and give information on the isotopic chains studied The description, although classified according to the technique used, follow to a large extent the chronological order. 

The elements in which long isotopic chains have been subject to hfs and IS measurements at ISOLDE are indicated in Fig 3 Here, we will choose two nuclear regions for short comments the rare-earth region and the "heavy-radium" region. 

Nuclear chart including the major shell closures and approximative isodeformation curves for e = 0.2. Hfs and IS measurements have been performed at ISOLDE in long isotopic chains of the elements indicated by arrows. Shorter sequences of the elements 35Br, 53I, 0gTm and glTl, not indicated here, have also been studied at ISOLDE. 

Fruitful discussions with members of the different hfs groups at ISOLDE, and in particular those with Dr. R. Neugart, are gratefully acknowledged. 

RAV84] H.L. Ravn, Proc. On-Line in 1985 and Beyond, Workshop on the ISOLDE Programme, Zinal, Switzerland (1984) p. D9. 

Most data on ground state properties of nuclei far from stability have been obtained at the on-line mass separator ISOLDE at CERN, where the isotopes of over 60 elements are available with high yields (up to 10 atoms per sec and mass number) and half lives down to 10 sec. [CER85]. Fig. 1 shows the chart of nuclei and indicates those regions where optical spectroscopy has been performed in long isotopic chains. Similar systematics of mass measurements have been restricted until now to the isotopes of the alkaline elements [AUD84]. 

This contribution concentrates on a discussion of some on-line techniques for ground state studies which are now under development and will be applied at ISOLDE in the near future. The plans for a nuclear-orientation set up at ISOLDE are outlined in the contribution to this symposium by N. Stone. 

USING THE ISOLDE-3 MASS SEPARATOR The high resolution of ISOLDE 3 (design value = 3.10 ) enables direct mass measurements. Such measurements were proposed at the Workshop "On-line in 1984 and beyond" held at Zinal [ZIN84]. In these experiments, the transmission signals have to be split in order to obtain the necessary accuracy. However, the feasibility of this technique has already been demonstrated by the Chalk River group [SHA84]. 

The experiment prepared for ISOLDE aims for a resolving power of 10 and an... 

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