Isolated from mangrove plant

Mangrove plants provide a source of compounds having physiological activity. The objective in this research has been the isolation and structure determination of the toxic compounds obtainable from the hexane extract of the dried roots of Herltlera llttoralls Dryland. 

A novel 7-membered ring compormd, (-)-3,4-dihydro-3-hydroxy-7-methoxy-2//-l,5-benzodithiepine-6,9-dione has been isolated from the stems of the mangrove plant Bruguiera sexangula var. rhynchopetala <05HCA2757>. 

The endophytic fungus Guignardia sp. No. 4382 was isolated from the Chinese mangrove plant K. candel. Besides the known vermistatin (70), two new derivatives 71 and 72, oxygenated at C-5, were reported. 70 was previously described as a metaholite from Penicillium vermiculaturnL When tested for cytotoxic properties, 70 was found to exhibit weak activity and 71 moderate activity, while both compounds were inactive when tested for antimicrobial activity toward one bacterial and two fungal strains. 

Kjer, J., Wray, V, Edrada-Ebel, R.A., Ebel, R., Pretsch, A., Lin, W, and Proksch, P. (2009) Xanalteric acid 1 and 11 and related phenolic compounds from an endophytic Altemaria sp. isolated from the mangrove plant Sonneratia alba. J. Nat. Prod., 72, 2053-2057. 

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