Ischaemia, bowel

Conceivably, such drugs might also find a place in the treatment of other forms of mesenteric ischaemia and also in the realms of small bowel transplantation. 

The theory underlying the pathophysiology of ischaemia-reperfusion injury, and the role of free radicals in this process has been discussed in detail above. The human colon contains relatively little XO (Parks and Granger, 1986) and so the arguments supporting a role for this enzyme in the pathogenesis of small bowel... 

Elderly people with diverticulosis may also have diffuse atherosclerotic vascular disease and thus are also at risk for ischaemic colitis. Ischaemic colitis is found frequently on the left side. Often the thickening is sharp bordered to the normal colon. A thickening with diminished vascularisation is highly suspicious for ischaemic colitis however, colour signals in a thickened bowel loop do not exclude ischaemia, since non-occlusive ischaemia may be present. 

Early diagnosis of small bowel volvulus is crucial for better outcome of management as it can prevent complications. The vascular occlusion can lead to ischaemia and gangrene of the bowel. The closed-loop obstruction may lead to tense disten-... 

A 49-year-old woman presented with acute abdominal pain and nausea. Abdominal CT scan revealed oedematous small bowel and ascites. She was thought to have intestinal ischaemia and was tiien subjected to a laparotomy which revealed that the intestine was vital with no perforation. ACEl-induced angioedema was suspected when a history of ingestion of lisinopril, 3 days prior to presentation was obtained. Lisinopril was replaced with amlodipine and the pain disappeared after 3 days. 

---