IPDI isophorone

In the multistep production of IPDI, isophorone is first converted to 3-cyano-3,5,5-trknethylcyclohexanone (231—235), then hydrogenated and ammoniated to 3-aminomethyl-3,5,5-trknethyl-l-aminocyclohexane (1) (236,237), also known as isophorone diamine (IPDA). In the final step IPDA is phosgenated to yield IPDI (2) (238). Commercial production of IPDI began in the United States in 1992 with the startup of Olin s 7000 t/yr plant at Lake Charles, Louisiana (239), and the startup of Hbls integrated isophorone derivatives plant in Theodore, Alabama (240). Hbls has a worldwide capacity for IPDA of 40,000 t/yr. 

IPDI Isophorone diisocyanate (3-isocyanatomethyl-3,4,4-triniethylcyclohexyl isocyanate... 

BRN 2726467 CCRIS 6252 Cyclohexane, 5-isocyanato-1-(isocyanatomethyl)-l,3,3-trimethyl- EINECS 223-861-6 HSDB 6337 IPDi Isophorone diamine diisocyanate Isophorone diisocyanate UN2290 Vestanat IPDI, Raw matenal for mfg. of light stable polyurethanes. Degussa-Huls Corp. 

Desmodur 1 Isocyanate-IPDI, isophorone diisocyanate (cycloaliphatic) Bayer... 

In certain niche applications, aliphatic isocyanates, such as isophorone diisocyanate (IPDI), hexamethylene diisoeyanate (HDI), methylene 4,4 -biscyclo-hexylisocyanate (H12MDI), and polymeric versions of these diisocyanates, are used, e.g., in instances where light stability or reduced reactivity is needed. These isocyanates usually cost more than the aromatic diisocyanates. Thus, they are used in adhesive areas that can Justify the higher costs. 

Polyurethane dispersions (PUD s) are usually high-performance adhesives based on crystalline, hydrophobic polyester polyols, such as hexamethylene adipate, and aliphatic diisocyanates, such as methylene bis(cyclohexyl isocyanate) (H12MDI) or isophorone diisocyanate (IPDI). These PUD s are at the more expensive end of the waterborne adhesive market but provide excellent performance. 

The ketimine of isophorone diamine is formed by reacting it with methyl isobutylketone, splitting off water in the process. When said ketimine is added to an isocyanate-terminated prepolymer based on IPDI, a semi-stable system is established with a pot life of several hours. The ketimine is a Schiff base and thus can react even in the absence of water. The complexities and advantages of this system are reviewed by Bock and Halpaap [75] ... 

Toxicology. Isophorone diisocyanate (IPDI) is an irritant and sensitizer of the respiratory tract and the skin. 

Lachapelle JM, Lachapelle-Ketelaer MJ Cross-sensitivity between isophorone diamine and isophorone diisocyanate (IPDI). Contact Derm 5 55, 1979... 

A study in mice examined immune responses following topical exposure to three allergenic diisocyanates diphenylmethane-4,4 -diisocyanate (MDI), dicyclohexyl-methane-4,4 -diisocyanate (HMDI), and isophorone diisocyanate (IPDI). Contact and respiratory sensitizers induce differential immune responses in mice characteristic of Thl and Th2 T helper cell activation, respectively. All three chemicals are contact allergens. MDI is, in addition, a known human respiratory allergen. HMDI and IPDI did not produce an immunologic response in the mouse similar to MDI. These findings suggest that HMDI has much less potential to cause respiratory sensitization in humans than does MDI ... 

A key factor in the preparation of polyurethanes is the reactivity of the isocyanates. Aromatic diisocyanates are more reactive than aliphatic diisocyanates, and primary isocyanates react faster than secondary or tertiary isocyanates. The most important and commercially most readily accessible diisocyanates are aliphatic and colorless hexamethylene-1,6-diisocyanate (HDI), isophorone diisocyanate (IPDI),and aromatic, brownish colored diphenylmethane-4,4 -diiso-cyanate (MDI), 1,5-naphthalenediisocyanate, and a 4 1 mixture of 2,4- and 2,6-toluenediisocyanates (TDI). 

The effect of curing on the diffusion of polymer and the curing agent is studied for the system of hydroxyl-terminated polybutadiene (R-45-M)/isophorone disso-cyanate (IPDI). Both components contribute to the echo intensity and the plot of In P(x)/I(0)] vs (G5)2 (A — 5/3) consists of two exponentials (Eq. (22)) the fast component (the steep intial slope) is attributed to the IPDI, and the long component to the R-45-M. The dependence of both diffusion constants on the curing time is shown in Fig. 19. The accuracy for Dfast data is less pronounced than for the polymer D(Mn), because only the first few data points are relevant for its determination. Furthermore, the low tail of the R-45-M molecular weight distribution nearly coin-... 

A trend in the utility of isophorone is as an important industrial building block. Foremost among these developments has been the use of isophorone as a raw material, and isophorone diisocyanate [2855-13-2] (IPDI), for the production of the light-stable polyurethane. The U.S. market for IPDI-based products was 31 million in 1989, and is estimated to grow to 53 million in 1994 (230). 

IPDI Isocyanate An abbreviation for isophorone diisocyanate. The name of the chemical group containing a nitrogen, carbon, and oxygen atom (-NCO). 

---