Intravascular glucose sensors

Armour JC. Long-term intravascular glucose sensors with telemetry. Artificial Organs 1989, 13, 171. 

J. Armour, J. Lucisano, and D. Gough, Application of chronic intravascular blood glucose sensor in dogs. Diabetes 39,1519-1526 (1990). 

Figure 4-17 Schematics of various implantable electrochemical/optical sensors useful for continuous in vivo monitoring (A) catheter style amperometric oxygen sensor (B) design of Paratrend intravascular combined PO2, PCO2, and pH sensor (hybrid electrochemical/optical design) (C) needle type electrochemical glucose sensor useful for monitoring glucose subcutaneously to track blood glucose levels continuously.

Yan, Q., Major, T.C., Bartlett, R.H., Meyerhoff, M.E., 2011. Intravascular glucose/lactate sensors prepared with nitric oxide releasing poly(lactide-cn-glycolide)-based coatings for enhanced biocompatibUity. Biosensors and Bioelectronics 26,4276-4282. 

Figure 5.34 Temporal traces of the calibrated GluCath intravascular continuous glucose sensor for two subjects with type 1 diabetes compared with results from a ABL Radiometer 805 Blood Gas Analyzer.

H. Zisser, Accuracy of a novel intravascular fluorescent continous glucose sensor, presented at the American Diabetes Association Meeting, New Orleans, LA, 2009. 

D. R. Markle and W. Markle, Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement using fluoro-phore assoed. with analyte-binding mol, Pat. W02008141241A1,2008. 

Figure 3.5 Cross section of boronate-afflnity sensor for intravascular glucose monitoring showing the bomonate gel-covering dialysis membrane and outer haemocompatible, heparin-coated microporous membrane.

With permission from Crane BC, Barwell NP, Gopal P, Gopichand M, Higgs T, James TD, et al. The development of a continuous intravascular glucose monitoring sensor. Journal of Diabetes Science and Technology 2015 9(4) 751-61. 

Romey, M., et al. (2012). Use of an intravascular fiuorescent continuous glucose sensor in subjects with type 1 diabetes mellitus (Translated from English). Journal of Diabetes Science and Technology, 6(6), 1260-1266 (in English). 

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