Integrated Scientific Information System

Integrated Scientific Information Systems (ISIS) MDL Information Systems Inc., San Leandro, USA. 

Molecular Design Limited (MDL) has marketed an Integrated Scientific Information System tlSISt. which provides the capability to query multiple systems, including binary, text, proprietary, and relational databases across glohal networks, thereby providing transparent deskiop access to multiple autonomous data sources. 

Integrated Scientific Information System for management of databases of 2D and 3D structures and associated properties on multiple platforms. PC (Windows), Macintosh, Fujitsu FMR, and NEC terminal support of ISIS/Draw and ISIS/Base ISIS/Desktop. Academic version of ISIS/Draw available from http //www.mdli.com/. ISIS SAR Table for outputting structure-activity data to Microsoft Excel. MACCS-II for managing and searching databases of 2D and 3D structures on a single platform. Fixed conformation and conforma-tionally flexible searching of 3D databases. Databases of structures three-... 

FIZ Chemie = Fachinformation.szentrum Cheniie ISl = institute for Scientific Information IRDAS = ISIS reaction database access system ISIS = integrated scientific information system JSM = Journal of Synthetic Methods MACCS = molecule access system MOS = Metlwd.s in Organic Synthesis, ORAC = Organic Reaction Acce.ss by Computer REACCS = Reaction Access System SMD = standard molecular data SPORE = Solid Phase Organic Reactions, STN = Scientific and Technical Information Network SYNLIB = Synthesis Library. 

The following is a synopsis of current scientific toxicity and fate information for the top chemicals (by weight) that facilities within this sector self-reported as released to the environment based upon TRI data. The information contained below is based upon exposure assumptions that have been conducted using standard scientific procedures. The effects listed must be taken in context of these exposure assumptions that are more fully explained within the full chemical profiles in the Hazardous Substances Data Bank (HSDB) and the Integrated Risk Information System (IRIS), both accessed via the Internet. 

IRIS (Integrated Risk Information System) http //toxnet.nlm. nih. gov/cgi-bin/sis/ htmlgen7IRIS.htm Online database of the Environmental Protection Agency (EPA http //www.epa.gov) containing carcinogenic and non-carcinogenic health risk information on over 500 chemicals. Data have been scientifically reviewed and represent EPA consensus. 

The authors thank the german research community (DFG) for the support of the presented investigations whieh were realized inside the Special Research Area 326, named, J rocess Integrated Quality Control with Quality Information System for Metallic Parts in Mechanical Engineering, and special thanks to the scientific bilateral project between Brazil and Germany supported by the CNPq, KFA and DLR to realize the presented investigations in advanced radioscopy and tomography. 

Inventories are basically structured knowledge repositories. They can be independent systems or alternatively can integrate data from other information systems. Information Technology (IT) tools are software applications that assist the user in specific operations. Some inventories and IT tools that can be considered as essential components of the DSS are described in generic terms below, with emphasis on their scientific features rather than to specific software applications (e.g., commercially available software). 

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