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Insulin gene expression alterations

Hofmann, C., Lorenz, K, Braithwaite, S. S., Colca, J. R., Palazuk, B.J., Hotamisligil, G. S., and Spiegelman, B. M. (1994). Altered Gene Expression for Tumour Necrosis Factor-A and Its Receptors During Drug and Dietary Modulation of Insulin Resistance. Endocrinology 134, 264—270. [Pg.209]

Oh YT, Oh KS, Choi YM, Jokiaho A, Donovan C, Choi S, Kang I, Youn JH (2011) Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue. Am J Physiol Endocrinol Metab 300 E1012-E1021... [Pg.298]

Gene expression may also be affected post-transcriptionally by altering mRNA levels. The insulin receptor has at least two splice variants termed type A or B. Exon 11 in the insulin receptor gene is spliced from the mRNA in the Type A variant and is associated with hyperinsulinemia. Over 30,000 alternative splice sites have been identified in a genome-wide analysis of humans, although functional polymorphisms at these sites have yet to be fully characterized. [Pg.25]

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See also in sourсe #XX -- [ Pg.188 ]



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Genes alteration

Insulin expression

Insulin genes

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