Innovative active ingredients

By bringing innovative active ingredients with novel modes of actions to the market makes it possible to offer new and attractive solutions to today s challenges in the agribusiness. 

Today, the concept of cosmetic is perceived by part of society as a necessity, a way to feel better about oneself and about others. However, cosmetic products are valued not simply for their pleasant textures and elegant feel, but also, very fundamentally, for their effectiveness. The idea that they are inert substances has totally disappeared. This new perception is largely due to the biological activity exerted by their innovative active ingredients. 

The way in which advanced research in pharmaceutical, nutraceutical and chemical products has influenced the cosmetics industry is increasingly significant and will continue to grow. This brief review of just a few of the many examples of innovative active ingredients used in cosmetics is only the tip of the iceberg as this exciting research will lead to huge advances in the effectiveness and safety of cosmetic products. 

Innovation in the area of chemicals is frequently reduced to the development of new substances. The registration of new substances and relevant market shares are thus interpreted as indicators of the innovation activity (or abihty to be innovative) in various economic areas". This indieator appears at best to be eapable of indicating essential aspeets of the iimovation history for the area of the active ingredients (pharmaceuticals and pesticides) and industrial special chemicals. In the extensive market of industrial ehemicals, on the other hand, the invention of new applications for old substances, the reformulation of preparations or the invention of new chemicals services should play a more important role. 

It should be evident that concurrent validation is especially useful as a QA tool. This approach to validation is useful to QA because it enables QA to set its own objectives as criteria for PV. For example, QA seeks to have every process validated. Most pharmaceutical products contain one or two active ingredients. Process validation is very straightforward for them however, a whole new situation exists for a multivitamin/multimineral product. Innovative techniques are thus needed to achieve adequate validation. 

The innovation deals with balanced nutrition in children of early age and their parents. The suggested food biologically active ingredient (BAA) includes powder of Jerusalem artichoke tubers. The food promotes the bitidogenic effect. 

By developing encapsulation methods, scientists and engineers mimic nature to obtain innovative structures to isolate, protect, release and functionalize active ingredients.1 However nature is not so easy to mimic, and what humans have developed are still inferior to what biological cells offer. 

Of all the new drug applications approved by the FDA between 1989 and 2000, by the estimate of the National Institute for Health Care Management (NIHCM), only one-third contained new active ingredients that could—even by a generous description—be considered innovative. (The pharmaceutical industry challeges the objectivity of the NIHCM, a nonprofit foundation, because it is heavily funded by the insurance industry, which has a natural bias toward low drug prices.)... 

For these reasons, direct compression has been most widely adopted by manufacturers of generic (i.e., non-innovative) pharmaceuticals. During the time when the active ingredient is covered by patent protection, its optimum manufacturing process will have been achieved, and so subsequent batch-to-batch variation in its physical properties ought then to be minimal. 

By using its own active ingredient, in the case of an innovator and by submitting a certificate of analysis covering all the raw material parameters reflected in the raw material specifications, covering the aspects reflected in the outline of the method of synthesis. 

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