Inline sensor system

Automation 13 [A 13] Combination of Inline Sensors with Electronic and Fluidic Bus System... 

A combined approach for the integration of inline sensors with an electronic and fluidic bus system is presented in the following. This development aims at the further intensification of plant compactness using the above-mentioned backbone concept of the pChemTec consortium [24], The goal was the reduction or complete avoidance of cables and wires which connect sensors in a plant to the peripheral data processing system by the supply of an internal wiring scheme, the internal electronic bus [86],... 

Fig. 11 Overview of the possible uses for a multiplexed microfluidic cell culture system. Input can be used for control of the stem cell nice and drug testing. The gradient generator creates a concentration profile of the input factors. The cell culture chamber is a perfusion chamber. Analysis involves monitoring the output of the device, which can include imaging with appropriate biomarkers, analysis using Inline sensors or standard laboratory equipment [74]...

Following the initial feasibility studies of Lubbers and Opitz, Cardiovascular Devices (GDI, USA) developed a GasStat extracorporeal system suitable for continuous online monitoring of blood gases ex vivo during cardiopulmonary bypass operations. The system consists of a disposable plastic sensor connected inline with a blood loop through a fiber optic cable. Permeable membranes separate the flowing blood from the system chemistry. The C02-sensitive indicator consists of a fine emulsion of a bicarbonate buffer in a two-component silicone. The pH-sensitive indicator is a cellulose material to which hydroxypyrene trisulfonate (HPTS) is bonded covalently. The 02-sensitive chemistry is... 

In this work, two optical particle measurement systems, on the basis of Statistical Extinction Method, have been developed. The Statistical Extinction Sensor (SE-Sensor) determines a mean particle size and a particle concentration inline in particle processes. Eor this purpose, the temporal course of the transmission of a light beam through the particle collective is measured and the mean particle size and the concentration are determined according to the Statistical Extinction Method (SE-Method). The PSD-SE-Sensor measures the temporal course of the transmission of nine light beams with different beam cross sections and determines a particle size distribution and concentration according to an extended Statistical Extinction Method (PSD-SE-Method). 

The (logical) access path to the equipment is considered on a very abstract level in K-RAMP. With respect to the control input, aforementioned instructions are applied. In terms of process results (process data, inline metrology data, quality assurance data) K-RAMP does not care about the mapping from the production system s sensors to process parameters but assumes that there is a rather product-independent (see previous section) mapping concept between the production system and the process segments already in place. Therefore, K-RAMP only focuses on parameters which are collected on the level of process segments and does not care about specific production system sensors or sensor busses. 

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