Inflammatory response vitamin

Shvedova, A.A. et al. (2007) Vitamin E deficiency enhances pulmonary inflammatory response and oxidative stress induced by single-walled carbon nanotubes in C57BL/6 mice. Toxicology and Applied Pharmacology, 221 (3), 339-348. 

Aukrust, P., Mulle, F., Ueland, T., Svardal, A. M., Berge, R. K., and Froland, S. S. (2000). Decreased vitamin A levels in common variable immunodeficiency Vitamin A supplementation in vivo enhances immunoglobulin production and downregulates inflammatory response. Eur. J. Clin. Invest. 30, 252-259. 

Ascorbic Acid Deficiency. Scurvy is the classical disease associated with ascorbate deficiency. It is a disease of the connective tissue and probably is caused by inadequate crosslinking attributed to a lack of hydroxy-lated proline and lysine. Many consider scurvy to be an advanced stage of ascorbate deficiency. Chronic deficiencies may also (l)in-crease risk for malignancies, as evidenced by oxidized DNA markers and increased concentrations of reactive oxygen species (2) decreased immune function, as evidenced by less vitamin in neutrophils and lymphocytes (3) cardiovascular disease caused by the inflammatory response on the blood vessel walls and (4) cataract formation caused by decreased concentrations of ascorbate in the ocular tissues. 

Murine model of pulmonary eosinophilic inflammation airway inflammation augmentation of allergen-induced T cell proliferation, increased Th2 cytokine (IL-4 and IL-13) and IgE production local inflammatory response ameliorated with impaired recruitment of eosinophils and inferior levels of IL-5 vitamin D could sustain Th2 response, leading to increased prevalence of allergy, but promising beneficial effects in airway eosinophilia [127]... 

Recently it was recognized that COX-1 provides eicosinoids for homeostatic purposes, while it is COX-2 that is inducible and generates prostaglandins for production of leukotrienes and induction of the inflammatory response. Now there is a major effort, with the first drugs already in use, to develop specific inhibitors for COX-2, which do not inhibit COX-1. It is hoped that these will be safer than However, these drugs can also cause dangerous side effects. COX-2 of macrophages is also inhibited by y-tocopherol, a major form of vitamin... 

In food products, vitamins are mainly added to replace losses in processing, or to fortily the product, but are also used as antioxidants or colourants. In the pharmaceutical industry, vitamins are used in supplement preparations such as tablets or capsules. Vitamins are also used in the cosmetics industry in skin care, hair care and oral hygiene products. Vitamins have been added to skin care products to boost the skin s antioxidant or anti-inflammatory response. They also function as immune system strengtheners, clarifiers or wrinkle redncers. 

The relationship of vitamin D to cardiovascular disease is finally being understood. l,25(OH)2D inhibits the production of the blood pressure hormone renin. It also alters cardiomyocyte growth and modulates the inflammatory response of atherosclerosis (Figure 7). 

Non-response to epoetin alfa therapy should prompt a search for causative factors. These include iron, folate, or vitamin B12 deficiency aluminium intoxication intercurrent infections inflammatory or traumatic episodes occult blood loss haemolysis and bone marrow fibrosis of any origin. 

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