Inflammatory demyelinating

Seroconversion neuropathy Inflammatory demyelinating neuropathy Early pre-AIDS Acute Generalized systemic dlness, mononeuropathies Immune dysfunction... 

Acute inflammatory demyelinating polyradiculopathy Early pre-AIDS Acute Motor to sensory signs NCS show demyelinating features Immune dysfunction complement/macrophage-mediated demyelinating neuropathy... 

Guillain-Barre syndrome is a transient neurologic disorder involving inflammatory demyelination of the peripheral nerves. The syndrome is characterized by progressive symmetric weakness of the legs and arms with loss of reflexes. Occasionally sensory abnormalities and paralysis of respiratory muscles will occur.16... 

Acute inflammatoiy demyelinating polyneuropathy is a common cause of reversible paralysis. Acute inflammatory demyelinating polyneuropathy (AIDP), the classic form of the Guillain-Barre syndrome, often begins a week or two after recovery from cytomegalovirus, Epstein-Barr virus or Mycoplasma infection. Patients present with rapidly advancing symmetrical weakness, loss of deep tendon reflexes, often with distal numbness, and limb or back pain. Cerebrospinal fluid (CSF) protein concentration is elevated, but in most cases there is little or no increase in number of inflammatory cells in the CSF. This albumino-cytologic dissociation contrasts with the elevation of both... 

Magira, E. E., Papaioakim, M., Nachamkin, I. et al. Differential distribution of HLA-DQP/DRP epitopes in the two forms of Guillain-Barre syndrome, acute motor axonal neuropathy and acute inflammatory demyelinating... 

Once the monoclonal antibodies reacting with complex glycolipids were shown to occur frequently in patients with neuropathy in association with gammopathy, antibodies were demonstrated in some patients with GBS and other forms of inflammatory demyelinating neuropathy [21]. 

Kieseier, B. C., Dalakas, M. C. and Hartung, H. P. Immune mechanisms in chronic inflammatory demyelinating neuropathy. Neurology 59, S7-S12, 2002. 

PARK p-adrenergic receptor kinase CIDP chronic inflammatory demyelinating polyneuropathy... 

Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the central nervous system (CNS), affecting... 

Chronic inflammatory demyelinating polyneuropathy is sometimes associated with malignancy [123]. The reported incidence of carcinoma in chronic inflammatory demyelinating polyneuropathy varies from 4 to 10% [100, 124]. 

Elderly patients with chronic inflammatory demyelinating polyneuropathy and a subacute onset and poor response to treatment are particularly prone to harboring an underlying malignancy [125],... 

Antoine JC, Mosnier JF, Lapras J, Convers P, Absi L, Laurent B, et al. Chronic inflammatory demyelinating polyneuropathy associated with carcinoma. J Neurol Neurosurg Psychiatry 1996 60(2) 188-190. 

Multiple sclerosis (together with other idiopathic inflammatory demyelinating diseases) is an autoimmune and multifactorial disorder. 

UccelH A, Zappia E, Benvenuto F, Frassoni F, Mancardi G (2006) Stem cells in inflammatory demyelinating disorders A dual role for immunosuppression and neuroprotection. Expert Opin Biol Tlrer 6 17-22. 

Guillain-Barre Syndrome, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, and Axonal Degeneration and Regeneration... 

Bosboom WMJ, Van den Berg LH, Mollee I, Sasker LD, Jansen J, Wokke JHJ, Logtenberg T (2001b) Sural nerve T-cell receptor V beta gene utilization in chronic inflammatory demyelin-ating polyneuropathy and vasculitic neuropathy. Neurology 56 74-81. 

Axonal injury may occur not only in the late phases of MS but also after early episodes of inflammatory demyelination (Lucchinetti et al., 1999 Trapp et al., 1998 Bitsch et al., 2000 De Stefano et al., 2001). Gray matter lesions and axonal injury in normal appearing w hite matter are reported in MS implying that axonal injury could trigger demyelination (Tsunoda and Fujinami, 2002). The pathogenesis of this early axonal injury is still unclear. 

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