Inflammatory bowel disease idiopathic

There are two forms of idiopathic inflammatory bowel disease (IBD) ulcerative colitis, a mucosal inflammatory condition confined to the rectum and colon, and Crohn s disease, a transmural inflammation of GI mucosa that may occur in any part of the GI tract. The etiologies of both conditions are unknown, but they may have a common pathogenetic mechanism. 

Other etiologies Congenital, idiopathic, hereditary (trypsinogen gene mutations), cystic fibrosis, inflammatory bowel disease, peptic ulcer disease, solid organ transplantation (liver, kidney, heart), refeeding... 

The idiopathic inflammatory bowel disease includes ulcerative colitis and granulomatous disease of the gastrointestinal tract (Crohn s disease). The newer derivatives of 5-aminosalicylic acid, namely balsalazine, sulfasalazine, or olsalazine, may be effective for treating ulcerative colitis but not Crohn s disease. 

Immune Modulating Therapies for Idiopathic Inflammatory Bowel Diseases Douglas S. Levine... 

TABLE 184 Idiopathic Inflammatory Bowel Disease Models... 

Chronic eosinophilic pneumonia Acute eosinophilic pneumonia Lymphangioleiomyomatosis Langerhans cell histiocytosis Idiopathic pneumonia syndrome Inflammatory bowel disease Cryoglobulinemia Primary biliary cirrhosis... 

The most common types of arthritis in the UK are osteoarthritis (UK prevalence 23%) and rheumatoid arthritis (1%). The less common t3 es of inflammatory arthritis include juvenile idiopathic arthritis spondylarthritis (ankylosing spondylitis, Reiter s syndrome, psoriatic arthritis, arthritis associated with inflammatory bowel disecise) and reactive arthritis associated with infection. Joint pains (arthralgia) are common in many other diseases, for example the connective tissue diseases (systemic lupus erythematosus, scleroderma), endocrine conditions (hypo-and h5 erthyroidism) and malignancies, but in these, joint inflammation and damage do not usually occur. 

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