Infectious pancreatic necrosis

Hong, J.R., Y.L. Hsu and J.L. Wu. Infectious pancreatic necrosis induces apoptosis due to down-regulation of survival factor MCL-1 protein expression in a fish cell line. Virus Res. 63 75-83, 1999. 

Birnavirus (infectious pancreatic necrosis virus of fish and infections bursal disease virus of fowl). 

WETTEN M, AASMUNDSTAD T, KJ0GLUM s and STORSET A (2007) Genetic analysis of resistance to infectious pancreatic necrosis in Atlantic sahnon Salmo solar L) , Aquaculture, vol. 272, pp. 111-117. 

Genetic management of the broodstock and progeny can improve the health of larvae. Selection of strains suitable for aquaculture often involves the inclusion of genes for rapid growth and slow maturation. It is only recently have attempts been made to include genes that enhance disease resistance. One good example is the resistance to infectious pancreatic necrosis (IPN) that one commercial supplier of Atlantic salmon applied to... 

SAiNTJEAN s R, MiNONDO M p V, PALACIOS M A and PRIETO s p (1991) Detection of infectious pancreatic necrosis in a carrier population of rainbow-trout, Oncorhynchus mykiss (RICHARDSON), by flow-cytometry. Journal of Fish Diseases, 14,... 

The compounds were tested for activity against two viruses with membranes. They were MCMV, a double stranded DNA herpes virus which replicates in the nucleus of mouse cells, and Sindbis virus (SV), a single-stranded RNA virus which replicates in many types of animal cells. The compounds were also tested on viruses without membranes phage T4 and fish infectious pancreatic necrosis virus (IPNV). Antiviral activity was observed only with ultraviolet activation. 

MCBEATH Aj, SNOW M, sEcoMBES cj, ELLIS AE, COLLET B (2007), Expression kinetics of interferon and interferon-induced genes in Atlantic salmon (Salmo salar) following infection with infectious pancreatic necrosis virus and infectious salmon anaemia virus , Eish Shellfish Immunol, 22,230-41. 

KBl HJ, OSEKO N, NiSHiZAWA T, YOSHiMizu M. Protection of rainbow trout from infectious hematopoietic necrosis (IHN) by injection of infectious pancreatic necrosis virus (IPNV) or Poly(I C). Dis Aquat Org 2009, 83,105-113. 

GIBSON D R, SMAiL D A and SOMMERVILLE c (1998), Infectious pancreatic necrosis virus experimental infection of goldsinny wrasse, Ctenolabrus rupestris L. (Labridae), / Fish Dis, 21, 399 06. 

MURRAY a g (2006), a model of the emergence of infectious pancreatic necrosis virus in Scottish salmon farms 1996-2003, Ecol Model, 199, 64-67. 

Pancreatic necrosis is a diffuse inflammation of the pancreas with infectious etiology. Pancreatic necrosis occurs within the first 2 weeks of acute pancreatitis and develops in 10% to 30% of patients with acute pancreatitis. The necrotic pancreas can become secondarily infected with enteric gramnegative bacteria (such as E. coli), and disseminated infection may result from pancreatic necrosis.7,8... 

Empiric antibiotics are not necessary if the patient has mild disease or a non-infectious etiology of acute pancreatitis. Antibiotics have not been shown to prevent the formation of pancreatic abscess or necrosis when given early in the course of acute pancreatitis. 

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