Infectious diseases soft tissue

Rheumatic disease is defined as disease of connective tissue and medical disorders of the musculoskeletal system . The medical discipline concerned with these diseases is referred to as rheumatology. The majority of rheumatic diseases are soft tissue rheumatism and nonspecific low back pain (LBP), autoimmune inflammatory rheumatic diseases, osteoarthritis (OA), osteoporosis, crystal-deposition disease and infectious arthritis. 

Stevens DL, Bisno AL, Chambers HF et al. (2005) Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clinical Infectious Diseases 41 1373-1406. 

Concomitant disease states may influence the selection of therapy. Certain diseases wfll predispose patients to a particular infectious disease or wfll alter the type of infecting organism. For example, patients with diabetes mellims and the resulting peripheral vascular disease often develop infections of the lower extremity soft tissue. Moreover, the alterations in peripheral blood flow associated with the disease and perhaps altered immunity make such infections more difficult to treat than in nondiabetics. Patients with chronic lung disease or cystic fibrosis develop frequent pulmonary infections that may be caused by somewhat different microorganisms than are found in otherwise normal hosts. 

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