Induced infiltration

Katiyar, S.K. and Mukhtar, H., Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress, J Leukoc Biol, 69, 719, 2001. 

There has been a previous report linking venlafaxine to pneumonia associated with eosinophilic infiltration, and SSRIs have been associated with drug-induced infiltrative lung disease. 

Chen, X., 2001, Migration of induced-infiltrated stream water into nearby aquifers due to seasonal ground water withdrawal Ground Water, v. 39, no. 5, p. 721-728. 

Wilson, J. L. (1993). Induced Infiltration in Aquifers with Ambient Flow. Water Resour. Res. 29(10), 3503-3512. 

Studies from our laboratoiy (Challa et al., 1998) have recently shown that GTP treatment amehorated UVB-induced oxidative burst as measured by H2O2 and myeloperoxidase production. GTP treatment to mice also partially blocked UVB-induced infiltration of leukocytes and appeared to inhibit lL-10 production in skin, as shown by immunohistochemistiy. In this study, GTP apphcation to mice prior to UVB irradiation was found to result in complete reversal of UVB-induced inhibition of contact hypersensitivity, but showed only partial reversal of induction of tolerance to 2,4-dinitrofluorobenzene. These data suggested that green tea, and the polyphenols present therein, might be useM against inflammatory dermatoses and immunosuppression caused by solar radiation in humans. The validation of these studies to human population exposed to low levels of UV radiation chronically through solar radiation is an area for further study. 

Nishikawa M, Kakemizu N, Ito T, Kudo M, Kaneko T, Suzuki M, Udaka N, Ikeda H, Okubo T. Superoxide mediates cigarette smoke-induced infiltration of neutrophils into the airways through nuclear factor-kappaB activation and IL-8 mRNA expression in guinea pigs in vivo. Am J Respir Crit Care Med 2000 161 1030-1036. 

An example of induced infiltration brought about by overpumping. The original hydraulic gradient over much of the area has been reversed so that pollutants can travel in the opposite direction, namely, towards the well. Additionally, the aquifer has become influent (i.e. water drains from the river into the aquifer) instead of effluent as it was originally. 

Intravenous injection of complete Freund s adjuvant induced infiltrative and follicular lesion in the rat lung, resembling human noncaseating granulomatoses of specific type in their localisation and cellular patter comparable in particular to sar-... 

Namiki M, Kawashima S, Yamashita T, et al. Local overexpression of monocyte chemoattractant protein-1 at vessel wall induces infiltration of macrophages and formation of atherosclerotic lesion synergism with hypercholesterolemia. Arterioscler Thromb Vase Biol 2002 22 115-120. 

Katiyar SK, Mukhtar H. Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes. 

Despite two centuries of research on SM in experimental animals and in humans, the animal studies are still ongoing. Mishra et al. (2010) showed that dermal SM exposure in euthymic hairless guinea pigs induced infiltration of both CD4+ and CD8+ T cells into the exposed skin. They also foxmd sfrong upregulated expression of... 

Chin JE, et al. Involvement of intercellular adhesion molecule-1 in the antigen-induced infiltration of eosinophils and lymphocytes into the airways in a murine model of pulmonary inflammation. Am J Respir Cell Mol Biol 1998 18(2) 158— 167. 

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