Influenza vaccines Indinavir

Clinically important, potentially hazardous interactions with amprenavir, aprepitant, bedomethasone, buprenorphine, calcium, chloramphenicol, cimetidine, dobazam, clorazepate, cyclosporine, cyproterone, darunavir, dasatinib, delavirdine, dexamethasone, diazoxide, disulfiram, dopamine, fesoterodine, fluconazole, flunisolide, fluoxetine, fosamprenavir, ginkgo biloba, hydrocortisone, imatinib, indinavir, influenza vaccines, isoniazid, isradipine, itraconazole, lacosamide, lapatinib, lopinavir, meperidine, methylprednisolone, midazolam, mivacurium, nelfinavir, nilotinib, nilutamide, phenylbutazone, piracetam, posaconazole, prednisolone, prednisone, primrose, ritonavir, rivaroxaban, sage, saquinavir, solifenacin, St John s wort, sucralfate, telithromycin, temsirolimus, teniposide, ticlopidine, tizanidine, tolvaptan, triamcinolone, uracil/tegafur, vigabatrin... 

Indinavir levels are raised by interleukin-2, but not affected by influenza vaccine or quinidine. Protease inhibitors are predicted to increase quinidine levels. Nelfinavir does not appear to interact with pancreatic enzyme supplements. In one case report, the combination of ritonavir/saquinavir and fusidic acid raised plasma levels of all three drugs. 

Influenza whole virus vaccine was given to 9 patients taking indinavir containing HAART. No significant changes were found in indinavir pharmacokinetics. ... 

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See also in sourсe #XX -- [ ]

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