In treatment of gastrointestinal

Sears HE, Atkinson B, Mattis J, Ernst C, Herlyn D, Steplewski A et al. Phase-1 clinical trial of monoclonal antibody in treatment of gastrointestinal tumours. Lancet 1982 1 762-5. [Pg.497]

Therapeutic effectiveness of copper complexes in treatment of gastrointestinal ulcers 500... [Pg.437]

THERAPEUTIC EFFECTIVENESS OF COPPER COMPLEXES IN TREATMENT OF GASTROINTESTINAL ULCERS... [Pg.500]

Quaternary alkaloid from many Berberis and Mahonia spp. (Berberidaceae) and very many other spp. in several different families. Pharmacol, extensively studied. Shows a wide variety of pharmacol. effects including respiratory stimulation, transient hypotension, convulsion. Cholinesterase, tyrosine decarboxylase and tryptophanase inhibitor. Antianaemic agent. Shows antibacterial and antifungal props, and some cytotoxic and antineoplastic activity. Of clinical use in treatment of gastrointestinal disorders, has been used for cholera and infantile diarrhoea. Of rel. low toxicity. [Pg.127]

Esters of diphenylacetic acids with derivatives of ethanol-amine show mainly the antispasmodic component of the atropine complex of biologic activities. As such they find use in treatment of the resolution of various spastic conditions such as, for example, gastrointestinal spasms. The prototype in this series, adiphenine (47), is obtained by treatment of diphenyl acetyl chloride with diethylaminoethanol. A somewhat more complex basic side chain is accessible by an interesting rearrangement. Reductive amination of furfural (42) results in reduction of the heterocyclic ring as well and formation of the aminomethyltetrahydro-furan (43). Treatment of this ether with hydrogen bromide in acetic acid leads to the hydroxypiperidine (45), possibly by the intermediacy of a carbonium ion such as 44. Acylation of the alcohol with diphenylacetyl chloride gives piperidolate (46). ... [Pg.91]

The work in this group has focussed mainly in antimony and bismuth because of the thermoelectric properties of the chalcogenides186 and as low temperature single-source precursors to related semiconductor materials.187 The use of bismuth compounds in the treatment of gastrointestinal disorders has lead to the study of several thiolate compounds as models to understand the bioactivity. [Pg.42]

Mahady GB, Pendland SL, Stoia A, Chadwick LR. (2005) In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother Res 19 988-991. [Pg.495]

Clinical use of reversible inhibitors is directed to eye, skeletal muscle, neuromuscular junctions, gastrointestinal tract, urinary tract, respiratory tract, and heart and used in treatment of glaucoma (an ocular disease caused by increased intraocular pressure due to inadequate drainage of aqueous humor at filtration angle), myasthenia gravis (an autoimmune disease... [Pg.186]

Tilhnan LA, Drake EM, Dixon JS, Wood JR. Review article safety of bismuth in the treatment of gastrointestinal diseases. Aliment Pharmacol Ther 1996 10(4) 459-67. [Pg.386]

ADH in larger dose increases the blood pressure by direct stimulation of vascular smooth muscle. It also stimulates the smooth muscle of gastrointestinal tract and increase the peristalsis. It is inactive orally because it is destroyed by trypsin. It can be administered by any parenteral route or by nasal spray. Vasopressin is indicated in diabetes insipidus and in treatment of postoperative abdominal varices. [Pg.210]

Anti metabolites are structural analogues of normal cellular constituents that interfere with the synthesis of purine and pyrimidine, which are essential for DNA synthesis and cell division. They are used in the treatment of gastrointestinal and pulmonary carcinomas as well as sarcomas and some leukaemias. The major toxic effects are bone marrow suppression, mucositis, severe diarrhoea, nausea and vomiting. They have been associated with acute and chronic hepatotoxicity. [Pg.249]

Chapter 62 Drugs Used in the Treatment of Gastrointestinal Diseases Chapter 63 Therapeutic Toxic Potential of Over-the-Counter Agents Chapter 64 Dietary Supplements Herbal Medications Chapter 65 Rational Prescribing Prescription Writing Chapter 66 Important Drug Interactions Their Mechanisms... [Pg.8]

AccessMedicine Print Chapter 62. Drugs Used in the Treatment of Gastrointestinal Diseases... [Pg.1309]

DRUGS USED IN THE TREATMENT OF GASTROINTESTINAL DISEASES INTRODUCTION... [Pg.1309]

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