Immunoglobulins class switching and

Alt, F.W., Rosenberg, N., Casanova, R.J., Thomas, E., Baltimore, D. (1982). Immunoglobulin heavy chain class switching and inducible expression in an Abelson murine leukaemia virus transformed cell line. Nature 296,325-331. 

Obata, M., Kataoka, T Nakai, S., Yamagishi, H., Takahashi, N., Yamawaki-Kataoka, Y., Nikaido, T., Shimizu, A., Honjo, T. (1981). Structure of a rearranged yl chain gene and its implication to immunoglobulin class-switch mechanism. Proc. Natl. Acad. Sci. USA 78,2437-2441. 

Harriman, W., Volk, H., Defranoux, N. and Wabl, M. (1993). Immunoglobulin class switch recombination. Annu. Rev. Immunol. 11, 361-384. 

Describe the phenomenon of class switching, and note its significance in maintaining constant recognition specificity among the immunoglobulin classes. 

Ehrenstein, M. R., and Neuberger, M. S. (1999). Deficiency in msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination parallels with somatic hypermutation. EMBO J. 18, 3484—3490. 

Imai, K., Slupphaug, G., Lee, W. I., Revy, P., Nonoyama, S., Catalan, N., Yel, L., Forveille, M., Kavli, B., Krokan, H. E., Ochs, H. D., Fischer, A., and Durandy, A. (2003b). Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination. Nat. Immunol. 4, 1023-1028. 

Kinoshita, K., Lee, C., Tashiro, J., Muramatsu, M., Chen, X., Yoshikawa, K., and Honjo, T. (1999). Molecular mechanism of immunoglobulin class switch recombination. Cold Spring Harb. Symp. Quant. Biol. 64, 217-226. 

Yu, K., and Lieber, M. (2003). Nucleic acid structures and enzymes in the immunoglobulin class switch recombination mechanism. DNA Repair 1163-1174. 

Yasui, H., Akahori, Y., Hirano, M., et al. (1989). Class switch from m to d is mediated by homologous recombination between sm and Sm sequences in human immunoglobulin gene loci. Eur. J. Immunol., 19, 1399-1403. 

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