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Immunogenicity glycoconjugates

Dell, A, Haslam, SM Morris, HR and Khoo, K-H (1999) Immunogenic glycoconjugates implicated in parasitic nematode diseases. Biochem Biophys Acta (In Press)... [Pg.1985]

New Zealand white rabbits (2-4 per immunogen) were injected (3-6 doses) at monthly intervals with the indicated saccharide-protein conjugate (10 yg/dose) or heat-killed j>. typhimurium SH4809 (1 x 10 bacteria/dose). The glycoconjugates were suspended 1 1 in Freund s complete adjuvant. [Pg.109]

However, it is evident that advances in immune system knowledge must be flanked by sound synthetic carbohydrate and glycoconjugate chemistry, which is still a challenging and hard task, even if the synthesis can now rely on efficient methods. It s not unreasonable to believe that, while carbohydrates themselves may not be particularly immunogenic, their conjugation to an appropriate multivalenced structure may work well. [Pg.527]


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Glycoconjugate

Glycoconjugates

Immunogene

Immunogenic

Immunogenicity

Immunogens

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