Immuno-liposome

Abra RM, Bankert RB, Chen F, et al. The next generation of liposome delivery systems recent experience with tumor-targeted, sterically-sbailized immuno-liposomes and active-loading gradients. J Liposome Res 2002 12 1-3. 

Mori, A., Klibanov, A. L., Torchilin, V. P., and Huang, L. (1991) Influence of the steric barrier activity of amphipathic poly (ethyleneglycol) and ganglioside GM1 on the circulation time of liposomes and on the target binding of immuno-liposomes in vivo. FEBS Lett. 284, 263-266. 

Khaw, B. A., Vural, I., Narula, J., and Torchilin, V. P. (1995) Targeted sealing of cell membrane lesions model of preservations of cell viability by immuno-liposome therapy. Proceedings of the 22nd International Symposium on Controlled Release of Bioactive Materials, Seattle, WA. Controlled Release Society, pp. 184-185. 

Mastrobattista E, Koning G A, van Bloois L, et al. (2002). Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immuno-liposome-entrapped proteins. J. Bioli. Chem. 277 27135-27143. 

Park J W, Benz C C, Martin F J (2004). Future directions of liposome- and immuno-liposome-based cancer therapeutics. Seminars Oncol. 6(suppl 13) 196-205. 

This group also includes immuno-analysis using liposomes, containing a liquid antigen in the membrane and tetrapentylammonium ion (TPA ) inside. The antibody causes immunolysis of the liposome and liberation of TPA, which is determined by an ISE [51]. 

Kim, Ch.K., Jeong, E.J. Development of dried liposomes as effective immuno-adjuvants for hepatitis B surface antigen. bit./. Pharm. 115,193-199,1995... 

Weiner, A.L. Liposomes for protein delivery. Immuno-methods 1994, 4, 201-209. 

Obenauer-Kutner, L.J. Jacobs, S.J. Kolz, K. Tobias, L.M. Bordens, R.W.A. A highly sensitive electrochemiluminescence immunoassay for interferon alfa-2b in human serum. J. Immunol. Meth. 1997, 206 (1-2), 25-33. Rabbany, S.Y. Donner, B.L. Ligler, F.S. Optical immuno-sensors. Crit. Rev. Biomed. Eng. 1994, 22 (5-6), 307-346. Wink, T. van Zuilen, S.J. Bull, A. van Bennekom, W.P. Liposome-mediated enhancement of the sensitivity in immunoassays of proteins and peptides in surface plasmon resonance spectrometry. Anal. Chem. 1998, 70 (5), 827-832. Gaudin, V. Pavy, M.-L. Determination of sulfamethazine in milk by biosensor immunoassay. J. AOAC Int. 1999, 82 (6), 1316-1320. 

Liposomal amphotericin has been given to an immuno-suppressed renal transplant patient with cerebral aspergillosis for almost 10 months at a cumulative dose of 42 g with no apparent changes in the function of the renal... 

Harokopakis E, Cholders NK, Michalek SM, et al. (1995) Conjugation of cholera toxin or its B subunit to liposomes for targeted delivery of antigens. In J. Immuno-log. Math. 185 31 -42. 

Moghimi SM. The effect of methoxy-PEG chain length and molecular architecture on lymph node targeting of immuno-PEG liposome. Biomaterials 2006 37 136-144. 

Wassef NM, Alving CR, Richards RL. Liposomes as carriers for vaccines. Immuno-methods 1994 Jun 4(3) 217-222. 

Figure 23.9 Schematic representation of the operation of a liposomal immuno-diagnostic assay for the detection of folic acid.

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