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Cytosolic delivery

Tardif MR, Tremblay MJ. Presence of host ICAM-1 in human immunodeficiency virus type 1 virions increases productive infection of CD4+ T lymphocytes by favoring cytosolic delivery of viral material. J Virol 2003 77(22) 12299-12309. [Pg.290]

Saito G, Amidon GL, Lee KD (2003) Enhanced cytosolic delivery of plasmid DNA by a sulfhydryl-activatable listeriolysin O/protamine conjugate utilizing cellular reducing potential. Gene Ther 10 72-83... [Pg.27]

Vasir JK, Labhasetwar V (2007) Biodegradable nanoparticles for cytosolic delivery of therapeutics. Adv Drug Deliv Rev 59 718-728... [Pg.57]

Hu Y, Litwin T, Nagaraja AR et al (2007) Cytosolic delivery of membrane-impermeable molecules in dendritic cells using pH-responsive core-shell nanoparticles. Nano Lett 7 3056-3064... [Pg.62]

The use of photochemical treatment to stimulate translocation of endocytosed macromolecules into the cytosol is a novel technology to improve therapeutic efficacy. The technology as described in this review is derived from photodynamic therapy (PDT) and is named PCI. In both cases a photosensitizer is used in combination with light to exert the treatment effects. The basic mechanisms of the photosensitizers and their tissue interaction in combination with light will be described with emphasis on the properties of the photosensitizers used in PCI before describing the use of PCI for cytosolic delivery of macromolecules. [Pg.253]

Mastrobattista E et al (2002) Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins. J Biol Chem 277 27135-27143... [Pg.24]

Asokan A, Cho MJ (2003) Cytosolic delivery of macromolecules. II. Mechanistic studies withpH-sensitive morpholine lipids. Biochim Biophys Acta 1611 151-160... [Pg.25]

Jana SS et al (2002) Targeted cytosolic delivery of hydrogel nanoparticles into HepG2 cells through engineered Sendai viral envelopes. FEES Lett 515 184-188... [Pg.27]

The choice of the phospholipid is dependent on the actual needs of the antigen delivery system. Cationic lipid with a combination of pH-sensitive lipid can be used for DNA-based vaccines delivery or intracellular cytosolic delivery of protein molecules. They may also be used in combination vaccines or in combination with other adjuvants like MPL-A (monophosphoryl lipid A), and cytokines (IL-2, IL-4, IFN-gamma). [Pg.187]

Direct Cytosolic Delivery Across the Plasma Membrane... [Pg.279]

DIRECT CYTOSOLIC DELIVERY ACROSS THE PLASMA MEMBRANE... [Pg.287]

See other pages where Cytosolic delivery is mentioned: [Pg.32]    [Pg.51]    [Pg.51]    [Pg.52]    [Pg.117]    [Pg.319]    [Pg.269]    [Pg.1164]    [Pg.11]    [Pg.214]    [Pg.215]    [Pg.349]    [Pg.350]    [Pg.352]    [Pg.279]    [Pg.279]    [Pg.279]    [Pg.280]    [Pg.280]    [Pg.282]    [Pg.283]    [Pg.284]    [Pg.284]    [Pg.285]    [Pg.286]    [Pg.286]    [Pg.287]    [Pg.288]    [Pg.290]    [Pg.290]    [Pg.290]    [Pg.291]    [Pg.291]    [Pg.291]    [Pg.292]   
See also in sourсe #XX -- [ Pg.51 ]

See also in sourсe #XX -- [ Pg.333 ]



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