Immobilization systems resin properties

Immobilization of GpdQ on modified magnetite nanoparticles and of biomimetics attached to resins will be presented. Comprehensive characterization of activity and properties of the immobilized systems will be conducted as a starting point for future applications of these systems in bioremediation (Chap. 8). 

Further simplification was attained by immobilization of the catalyst on a solid polymer (49), so that its separation from the product was reduced to mere mechanical filtration the resin bound catalyst could then be used for another run. Ofthe number of polymeric supports investigated, Merrifield (49) and Wang resins were identified as most suitable, exhibiting the same behavior and efficiency [18]. However, owing to the heterogeneous nature of the system, the enantioselectivity of the reaction decreased by 10 15% ee (Table 4.11, entries 6 12). In view ofthe swelling properties, toluene was found to be less suitable than chloroform (compare entries 6 and 7), which makes the method less environment friendly. Furthermore, a conditioning effect was observed for these systems the second run was always found to be more enantioselective than the first one by 10% ee and this level was maintained in the subsequent runs (compare entries 7 with 8 12). The latter effect stems from the... 

The final chapter deals with the immobilization of the systems on solid supports. Two supports were chosen due to their availability and favorable properties. Merrifield resin was used to immobilize NH2HL2 and CH3HL4 and their Zn(II) complexes generated. Successful immobilization was supported with IR, XPS and microanalysis measurements. The complexes were shown to be active towards organophosphates and provide promising systems for the use in filter systems. 

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