Imaging, body composition

Two imaging systems, dual energy X-ray absorptiometry scanning (DEXA) and magnetic resonance imaging (MRI), allow for longitudinal studies of whole body composition. DEXA measures bone mineral density and content, fat content, and lean content in anesthetized mice. Echo MRI from Echo Medical System, Houston, TX, is used to measure whole body composition parameters such as total body fat, lean mass, body fluids, and total body water in live mice without the need for anesthesia or sedation (15). The MRI technology is more rapid, less than a minute to scan one mouse, than DEXA which takes about 5 min per mouse. 

In addition, the ability to optimize biosensor design is of central importance and initially depends on the determination of what aspects of the foreign body reaction and biosensor surface properties are critical to the success of the implanted biosensor. To accomplish this efficiently, it would be very beneficial if active sensors could be imaged in situ. Thus, sensor performance could be quantified relative to the manipulation of local tissue and microvascular conditions in response to various implant properties. Some important implant features include surface texture, porosity, and surface material composition. Surface texture of the implant has been observed to affect the extent of collagen formation. Smooth implant surfaces, which the local... 

Beale AM, Jacques SDM, Bergwerff JA, Barnes P, Weckhuysen BM. Tomographic energy dispersive diffraction imaging as a tool to profile in three dimensions the distribution and composition of metal oxide species in catalyst bodies. Angew Chem Int Ed. 2007 46 8832. 

Vane, G., Duval, J. E. Wellman, J. B. (1993) Imaging spectroscopy of the earth and other solar system bodies. In Remote geochemical analysis elemental and mineralogical composition (ed. C. M. Pieters and P. A. J. Englert), pp. 121-143. Cambridge University Press, Cambridge. 

---