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Imaging angiogenesis

Hauhner RH, Wester HJ, Weher WA, Schwaiger M. Radiotracer-based strategies to image angiogenesis. Q J Nucl Med 2003 47 189-199. [Pg.440]

Santos AF, Zaltsman AB, Martin RC et al (2008) Angiogenesis an improved in vitro biological system and automated image-based workflow to aid identification and characterization of angiogenesis and angiogenic modulators. ASSAY Drug Devel Technol 6 693-710... [Pg.121]

R. Haubner, H.J. Wester, Radiolabeled tracers for imaging of tumor angiogenesis and evaluation of anti-angiogenic therapies, Curr. Pharm. Des. 10(13) (2004) 1439-1455. [Pg.192]

R. Hoffman, Green fluorescent protein imaging of tumour growth, metastasis, and angiogenesis in mouse models. Lancet Oncol. 3 (2002) 546-556. [Pg.256]

J.G. Rajendran, K.A. Krohn, Imaging hypoxia and angiogenesis in tumors, Radiol. Clin. North Am. 43 (2005) 169-187. [Pg.271]

Fox, S. B., Leek, R. D., Weekes, M. P., Whitehouse, R. M., Gatter, K. C., and Harris, A. L. 1995. Quantitation and prognostic value of breast cancer angiogenesis Comparison of microvessel density, chalkley count and computer image analysis. J. Pathol. 777 275-283. [Pg.316]

Noninvasive detection of vascular abnormalities is of the utmost importance in clinical imaging. Indeed, a lot of injuries and diseases manifest themselves through modifications of the vasculature [1,2]. For example, abnormal angiogenesis (blood vessel growth) is observed in the development of most tumors. Embolism and atherosclerosis also manifest themselves through alterations of the blood vessels, namely through occlusions. Hemorrhage could also be detected noninvasively, which is crucial in injuries or in diseases such as ulcers [1]. [Pg.127]

In numerous animal models, it has reportedly promoted angiogenesis, improved myocardial perfusion, and acutely improved endothelial vasodilatory function. In the present study, we report the impact of the administration of recombinant FGF-2 (rFGF-2) on stress and rest myocardial perfusion using gated SPECT myocardial perfusion imaging in a phase I trial in humans with advanced symptomatic coronary artery disease. [Pg.394]

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Angiogenesis

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