IDEALS project

Figure 1. Idealized projection of the building units of the faujasite framework...

DISCO considers three-dimensional conformations of compounds not as coordinates but as sets of interpoint distances, an approach similar to a distance geometry conformational search. Points are calculated between the coordinates of heavy atoms labeled with interaction functions such as HBD, HBA or hydrophobes. One atom can carry more than one label. The atom types are considered as far as they determine which interaction type the respective atom would be engaged in. The points of the hypothetical locations of the interaction counterparts in the receptor macromolecule also participate in the distance matrix. These are calculated from the idealized projections of the lone pairs of participating heavy atoms or H-bond forming hydrogens. The hydrophobic points are handled in a way that the hydrophobic matches are limited to, e.g., only one atom in a hydrophobic chain and there is a differentiation between aliphatic and aromatic hydrophobes. A minimum constraint on pharmacophore point of a certain type can be set, e.g. if a certain feature is known to be required for activity [53, 54]. 

Computer image simulation may be achieved by several different techniques (12), but the most common method is the multislice calculation. In this method, input consists of a structural model, the projection direction through the structure, and parameters describing the electron microscope. Slight misorientations of the structure from the ideal projection direction may also be simulated. 

Ease of obtaining valid results. An ideal project provides a means to obtain guaranteed data for your report, but also the chance to extend knowledge by doing genuinely novel research. 

Fig. 1. Idealized projection and section through a sodalite 3-cage unit. (After Smith 1976.)...

Figure 9. Flow diagram (starting at an idealised sediment core) for the preparation of lacustrine sediment samples for the isotopic analysis of organic matter, emphasising the importance of integrating such studies with a range of other analytical techniques. Based in part on procedures u.sed by the International Decade for the East African Lakes (IDEAL) project (LRC, 1999).

This review would not have been possible without the help and inspiration provided by Tine Lsrdal, Mizzi Filippi and Niels Bo Jensen. All three are thanked for several years of fruitful collaboration and for valuable comments on earlier versions of this manuscript. Financial support for some of the work presented here has been provided by the Norwegian Research Council, Elf Norge, and NSF, via its support of the IDEAL project. Brent Wolfe... 

Typically, these were positioned in a triangle, with the perimeter of a circle representing the ideal project. Our experience in the field of safety management, coupled with the emergence of new legislation has led to add Safety, not as an add-on but as a genuine fourth objective within that circle (see Figure 2). 

There are considerable pedagogical benefits in combining groups of electrical and mechanical engineering senior students in a capstone project. The total design and construction of an industrial robot and its control system serves as an ideal project for such a combined group of students. This paper describes two "Build a Robot projects which have been carried out at West Virginia University. 

FIG. 25 A populated test board used throughout the IDEALS project for reflow and repair... 

The IDEALS project has succeeded in identifying suitable lead-free solder alloys and their matched fluxing systems, board finishes, and component metallization, which were tested in extensive assembly trials. The chosen solders were ... 

The Synthesis Report for the IDEALS project can be downloaded from. < http //www.alphametals. com/products/lead free/PDF/synthesis.pdf > < http //www.marconicaswell.com/tech/emtec.htm > < http //www.cordis.lu>. 

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